Invitrogen™ Cripto Monoclonal Antibody (3A6)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA515843

Catalog No. PIMA515843

Description

MA5-15843 targets TDGF1 in WB applications and shows reactivity with Human samples. The MA5-15843 immunogen is purified recombinant fragment of human TDGF1 expressed in E. Coli. .

Cripto (TDGF1) is a GPI-anchored cell membrane proetin involved in Nodal signaling. Cell associated TDGF1 acts as a a Nodeal coreceptor in cis. Shedding of TDGF1 by TMEM8A modulated Nodal signaling by allowing soluble TDGF1 to act as a Nodal coreceptor on other cells. TDGF1 is expressed both in ES cells and during the early phases of embryo development, while in adults it is reactivated in a wide range of epithelial cancers.

Specifications

• Antigen: Cripto
• Classification: Monoclonal
• Concentration: Conc. Not Determined
• Formulation: ascites with 0.03% sodium azide
• Gene Accession No.: P13385
• Gene Symbols: TDGF1
• Immunogen: Purified recombinant fragment of human TDGF1 expressed in E. Coli.
• Regulatory Status: RUO
• Gene ID (Entrez): 6997
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Western Blot
• Clone: 3A6
• Conjugate: Unconjugated
• Gene: TDGF1
• Gene Alias: CR; CR1; CRGF; CRIPTO; cripto growth factor; Cripto-1; cripto-1 growth factor; Cripto-3; epidermal growth factor-like Cripto protein; epidermal growth factor-like cripto protein CR1; Tdgf1; TDGF2; teratocarcinoma-derived growth factor; teratocarcinoma-derived growth factor 1; TERATOCARCINOMA-DERIVED GROWTH FACTOR PRECURSOR (EPIDERMAL GROWTH FACTOR-LIKE CRIPTO PROTEIN) (CRIPTO GROWTH FACTOR)
• Host Species: Mouse
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1