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Invitrogen™ HSF2 Recombinant Rabbit Monoclonal Antibody (JE48-40)
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Catalog No. PIMA534860
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100 μL
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PIMA534860 100 μL
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Catalog No. PIMA534860 Supplier Invitrogen™ Supplier No. MA534860
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Description

Rabbit Recombinant Monoclonal Antibody

Positive Control: Daudi, HepG2, human breast cancer tissue, human prostate cancer tissue, human skin tissue, human colon cancer tissue, human gastric cancer tissue, 293.

Prokaryotic and eukaryotic cells respond to thermal and chemical stress by inducing a group of genes collectively designated heat shock genes. In eukaryotes, this gene expression is regulated primarily at the transcription level. Heat shock transcription factors (HSF, also designated HSTF) 1 and 2 are involved in this regulation. HSF1 and HSF2 are upregulated by estrogen at both the mRNA and protein level. HSF1 is normally found as a monomer whose transcriptional activity is repressed by constitutive phosphorylation. Upon activation, HSF1 forms trimers, gains DNA binding activity and is translocated to the nucleus. HSF2 activity is associated with differentiation and development, and, like HSF1, binds DNA as a trimer. Both HSF1 and HSF2 are known to be induced by proteasome inhibitors of the ubiquitin pathway.
TRUSTED_SUSTAINABILITY

Specifications

Antigen HSF2
Applications Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Recombinant Monoclonal
Clone JE48-40
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation TBS with 40% glycerol, 0.05% BSA and 0.05% sodium azide; pH 7.4
Gene HSF2
Gene Accession No. Q03933
Gene Alias AI661205; heat shock factor 2; heat shock factor protein 2; Heat shock transcription factor 2; HSF 2; Hsf2; HSTF 2; HSTF2; MGC117376; MGC156196; MGC75048
Gene Symbols HSF2
Host Species Rabbit
Immunogen Recombinant protein within Human HSF2 aa 426-536.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 3298
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles, store in dark
Product Type Antibody
Form Liquid
Isotype IgG
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