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Invitrogen™ CRMP1 Polyclonal Antibody
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Catalog No. PIPA577924
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100 μL
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PIPA577924 100 μL
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Catalog No. PIPA577924 Supplier Invitrogen™ Supplier No. PA577924
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Description

Rabbit Polyclonal Antibody

Positive Control: MCF-7, mouse brain Predicted Reactivity: Rat (91%), Xenopus laevis (83%), Chicken (90%), Rhesus Monkey (98%), Bovine (94%) Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Collapsin-response mediator proteins (CRMPs) are highly expressed in the developing brain where they play major roles in axonal outgrowth, neurite differentiation, and apoptosis. Their continued expression in areas of high synaptic remodeling such as the cerebellum, hippocampus, and the olfactory system suggests that these proteins may also be involved in adult brain plasticity. CRMP-1 was initially identified as a dihydro-pyrimidinase expressed exclusively in brain; later studies have shown that it is involved with neurotrophin (NT) 3-induced neurite formation and outgrowth. CRMP-1 localization switches from axonal to somatodendritic when neurons reach functional maturity, suggesting that it is involved in early neuronal differentiation as well as in later processes related to the survival or death of the newly generated neurons.
TRUSTED_SUSTAINABILITY

Specifications

Antigen CRMP1
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 0.77 mg/mL
Conjugate Unconjugated
Formulation 0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7
Gene CRMP1
Gene Accession No. P97427, Q14194
Gene Alias Collapsin response mediator protein 1; Crmp1; CRMP-1; dihydropyrimidinase-like 1; dihydropyrimidinase-related protein 1; Dpysl1; DRP1; DRP-1; Ulip3; ULIP-3; Unc-33-like phosphoprotein 3
Gene Symbols CRMP1
Host Species Rabbit
Immunogen Recombinant protein encompassing a sequence within the C-terminus region of human CRMP1. The exact sequence is proprietary.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 12933, 1400
Target Species Human, Mouse
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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