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  5. Tocris Bioscience™ CS 640

Tocris Bioscience™ CS 640
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Catalog No. 798250
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Catalog No. Quantity
79-825-0 50 mg
79-821-0 10 mg
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Catalog No. 79-825-0 Supplier Tocris Bioscience™ Supplier No. 7982/50
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Description

Potent CaM kinase I inhibitor

CS 640 is a potent calmodulin-dependent kinase I (CaMKI) inhibitor (IC50 values are 1 nM, 1 nM, 3 nM and 8 nM at CAMK1A, CAMK1G, CAMK1B and CAMK1D respectively). Improves insulin sensitivity and glucose control in a mouse model of diet-induced obesity. Orally bioavailable in rodents.

Specifications

Chemical Name or Material 2-[(3S)-3-Amino-1-piperidinyl]-4-[[2,6-bis(1-methylethyl)-4-pyridinyl]amino]-5-pyrimidinecarboxamide
CAS 2388506-83-8
Quantity 50 mg
Target CaM Kinase I
Molecular Formula C21H31N7O
Purity 0.98
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