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Invitrogen™ GPS2 Polyclonal Antibody
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Catalog No. PIPA5101593
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100 μL
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PIPA5101593 100 μL
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Catalog No. PIPA5101593 Supplier Invitrogen™ Supplier No. PA5101593
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total GPS2.

This gene encodes a protein involved in G protein-mitogen-activated protein kinase (MAPK) signaling cascades. When overexpressed in mammalian cells, this gene could potently suppress a RAS- and MAPK-mediated signal and interfere with JNK activity, suggesting that the function of this gene may be signal repression. The encoded protein is an integral subunit of the NCOR1-HDAC3 (nuclear receptor corepressor 1-histone deacetylase 3) complex, and it was shown that the complex inhibits JNK activation through this subunit and thus could potentially provide an alternative mechanism for hormone-mediated antagonism of AP1 (activator protein 1) function.
TRUSTED_SUSTAINABILITY

Specifications

Antigen GPS2
Applications Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene GPS2
Gene Accession No. Q13227, Q921N8
Gene Alias AI505953; AMF-1; G protein pathway suppressor 2; GPS2; GPS-2
Gene Symbols GPS2
Host Species Rabbit
Immunogen A synthesized peptide derived from human GPS2(Accession Q13227), corresponding to amino acid residues R20-L70.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 2874, 497941, 56310
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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