Invitrogen™ CSP alpha Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA1776

Catalog No. APPG76

Description

PA1-776 detects Cysteine String Protein Alpha in mouse and rat brain samples. PA1-776 has been successfully used in Western blot procedures. By Western blot, this antibody detects a ~34 kDa protein representing Cysteine String Protein Alpha in rat and mouse brain homogenates. The PA1-776 immunogen is a synthetic peptide corresponding to residues E(180) T T Q L T A D S H P S Y H T D G F N(198) of rat CSP. This sequence is conserved across many species including mouse, human and bovine. This peptide (Cat. # PEP-287) is available for use in neutralization and control experiments.

Cysteine string protein alpha (CSPalpha) is a synaptic vesicle protein that contains a DNA-J domain characteristic of Hsp40 chaperones. Cysteine-string proteins are membrane-bound proteins associated primarily with nerve endings and synaptic vesicles in the brain. These proteins play an important role in presynaptic function and may be involved in calcium-dependent neurotransmitter release. CSP proteins may act as presynaptic chaperones that assist in maintaining synaptic function.

Specifications

• Antigen: CSP alpha
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Dnajc5
• Gene Alias: 2610314I24Rik; AU018536; Ceroid-lipofuscinosis neuronal protein 4; CLN4; CLN4B; Csp; CSP alpha; cysteine string protein; cysteine string protein alpha; DnaJ (Hsp40) homolog, subfamily C, member 5; DnaJ heat shock protein family (Hsp40) member C5; dnaJ homolog subfamily C member 5; Dnajc5; DNAJC5A; mir-941-2; mir-941-3; mir-941-4; mir-941-5; NCL
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 13002, 79130, 80331
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 1mg/mL BSA and 0.05% sodium azide
• Gene Accession No.: P60904, P60905, Q9H3Z4
• Gene Symbols: Dnajc5
• Immunogen: Synthetic peptide corresponding to residues E(180) T T Q L T A D S H P S Y H T D G F N(198) of rat CSP.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG