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CST2 Rabbit anti-Human, Polyclonal, Proteintech
SDP

Catalog No. 501732612 Shop All Proteintech Group Inc Products
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50-173-2612 150 μL
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Catalog No. 50-173-2612 Supplier Proteintech Group Inc Supplier No. 199351AP150UL
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Description

Rabbit Polyclonal Antibody

This antibody is specific to CST2.

The cystatin superfamily is a well-established family of cysteine protease inhibitors. Cystatins A and B (type 1) are mainly intracellular; cystatins C, D, E/M, F, G, S, SN and SA cystatins are extracellular (type 2); and the kininogens are type 3 cystatins which are intravascular proteins. All true cystatins inhibit cysteine peptidases of the papain family, such as cathepsins, and some also inhibit legumain family enzymes. Cystatin SA, cystatin S and cystatin SN are found primarily in saliva. Cystatin S and SN can also be expressed in tears, urine and seminal fluid. Cystatin C is a related protein which is expressed in brain, thymus, ovary, epididymis and vas deferens. Cystatin D protects against proteinases in the oral cavity, while Cystatin E/M and F moderate the inhibition of cathepsin proteins. The fetuins, part of the cystatin superfamily, are secretable proteins that influence osteogenesis and bone resorption, regulation of the insulin and hepatocyte growth factor receptors and the response to systemic inflammation. High molecular weight kininogen (Kininogen HC) and low molecular weight kininogen (Kininogen LC) have varied roles, though they both inhibit the thrombin- and plasmin-induced aggregation of thrombocytes.

Specifications

Antigen CST2
Applications Western Blot
Classification Polyclonal
Concentration 0.15 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Gene CST2
Gene Accession No. P09228
Gene Alias CST2, Cystatin 2, Cystatin S5, cystatin SA
Gene Symbols CST2
Host Species Rabbit
Immunogen Peptide
Purification Method Antigen Affinity Chromatography
Quantity 150 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 1470
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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