Invitrogen™ CTGF Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA532193

Catalog No. PIPA532193

Description

Recommended positive controls: A549, H1299, HCT116, HUVEC, Mouse heart, Rat bladder, CTGF-transfected 293T, HepG2, HepG2 conditioned medium. Predicted reactivity: Mouse (93%), Rat (94%), Xenopus laevis (85%), Pig (95%), Chicken (94%), Sheep (96%), Chimpanzee (99%), Bovine (93%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Connective Tissue Growth Factor (CTGF), also called CCN2, is a member of the CCN family. CTGF is a secreted protein produced by umbilical veins and vascular endothelial cells. CTGF possesses an Insulin-like Growth Factor (IGF)-binding domain, a thrombospondin type 1 domain, and a cysteine knot region. CTGF plays important roles in the proliferation and differentiation of chondrocytes, induces angiogenesis, and promotes cell adhesion in fibroblasts, endothelial, and epithelial cells.

Specifications

• Antigen: CTGF
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: CCN2
• Gene Alias: 2-Nov; betaIG-M2; CCN family member 2; Ccn2; Cellular communication network factor 2; connective tissue growth factor; connective tissue growth factor precursor; Connective tissue growth factor precursor (CTGF) (FISP-12 protein) (Hypertrophic chondrocyte-specific protein 24); connective tissue growth-related protein; CTGF; CTGF protein; CTGRP; fibroblast inducible secreated protein; fibroblast inducible secreted protein; Fisp12; fisp-12; Hcs24; H-CTGF; hypertrophic chondrocyte-specific gene product 24; hypertrophic chondrocyte-specific protein 24; IBP-8; IGF-binding protein 8; IGFBP8; IGFBP-8; Insulin-like growth factor-binding protein 8; MGC102839; NOV2; Protein FISP-12; similar to connective tissue growth factor precursor
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 14219, 1490, 281103, 64032
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 0.42 mg/mL
• Formulation: PBS with 1% BSA, 20% glycerol and 0.025% ProClin 300; pH 7
• Gene Accession No.: O18739, P29268, P29279, Q9R1E9
• Gene Symbols: CCN2
• Immunogen: Recombinant protein encompassing a sequence within the center region of human CTGF. The exact sequence is proprietary.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Baboon, Bovine, Human, Mouse, Monkey, Rat
• Product Type: Antibody
• Isotype: IgG