Invitrogen™ CTHRC1 Monoclonal Antibody (5H1)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA534885

Catalog No. PIMA534885

Description

Positive Control: CTHRC1 recombinant protein, rat large intestine tissue, human kidney tissue, human placenta tissue.

The Collagen triple helix repeat-containing protein (CTHRC1) is a glycosylated, secreted protein that is transiently expressed in the arterial wall in response to injury where it is thought to contribute to vascular remodeling by inhibiting collagen expression and deposition and promoting cell migration. CTHRC1 is highly expressed multiple human cancers, including pancreatic cancer where it plays a significant role in the progression and metastasis of the disease by regulating migration and adhesion of tumors cells. CTHRC1 overexpression can also be used as an independent prognostic marker in gastric cancer. Mutations at this locus have been associated with Barrett esophagus and esophageal adenocarcinoma.

Specifications

• Antigen: CTHRC1
• Classification: Monoclonal
• Concentration: 2.0 mg/mL
• Formulation: PBS with 0.2% BSA, 50% glycerol and 0.05% sodium azide; pH 7.4
• Gene Accession No.: Q96CG8
• Gene Symbols: Cthrc1
• Immunogen: Recombinant protein within Human CTHRC1 aa 1-243.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Clone: 5H1
• Conjugate: Unconjugated
• Gene: Cthrc1
• Gene Alias: 1110014B07Rik; collagen triple helix repeat containing 1; collagen triple helix repeat-containing protein 1; CTHRC1; Protein NMTC1; UNQ762/PRO1550
• Host Species: Mouse
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 115908
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles, store in dark
• Form: Liquid