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Invitrogen™ CTHRC1 Monoclonal Antibody (5H1)
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Catalog No. PIMA534885
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100 μL
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PIMA534885 100 μL
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Catalog No. PIMA534885 Supplier Invitrogen™ Supplier No. MA534885
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Description

Mouse Monoclonal Antibody

Positive Control: CTHRC1 recombinant protein, rat large intestine tissue, human kidney tissue, human placenta tissue.

The Collagen triple helix repeat-containing protein (CTHRC1) is a glycosylated, secreted protein that is transiently expressed in the arterial wall in response to injury where it is thought to contribute to vascular remodeling by inhibiting collagen expression and deposition and promoting cell migration. CTHRC1 is highly expressed multiple human cancers, including pancreatic cancer where it plays a significant role in the progression and metastasis of the disease by regulating migration and adhesion of tumors cells. CTHRC1 overexpression can also be used as an independent prognostic marker in gastric cancer. Mutations at this locus have been associated with Barrett esophagus and esophageal adenocarcinoma.
TRUSTED_SUSTAINABILITY

Specifications

Antigen CTHRC1
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Monoclonal
Clone 5H1
Concentration 2.0 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.2% BSA, 50% glycerol and 0.05% sodium azide; pH 7.4
Gene Cthrc1
Gene Accession No. Q96CG8
Gene Alias 1110014B07Rik; collagen triple helix repeat containing 1; collagen triple helix repeat-containing protein 1; CTHRC1; Protein NMTC1; UNQ762/PRO1550
Gene Symbols Cthrc1
Host Species Mouse
Immunogen Recombinant protein within Human CTHRC1 aa 1-243.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 115908
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles, store in dark
Product Type Antibody
Form Liquid
Isotype IgG1
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