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Invitrogen™ CTHRC1 Polyclonal Antibody
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Catalog No. PA549638
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400 μL
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PA549638 400 μL
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Catalog No. PA549638 Supplier Invitrogen™ Supplier No. PA549638
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Description

Rabbit Polyclonal Antibody

CTHRC1 Polyclonal Antibody for Flow, IHC (P), Western Blot

The Collagen triple helix repeat-containing protein (CTHRC1) is a glycosylated, secreted protein that is transiently expressed in the arterial wall in response to injury where it is thought to contribute to vascular remodeling by inhibiting collagen expression and deposition and promoting cell migration. CTHRC1 is highly expressed multiple human cancers, including pancreatic cancer where it plays a significant role in the progression and metastasis of the disease by regulating migration and adhesion of tumors cells. CTHRC1 overexpression can also be used as an independent prognostic marker in gastric cancer. Mutations at this locus have been associated with Barrett esophagus and esophageal adenocarcinoma.
TRUSTED_SUSTAINABILITY

Specifications

Antigen CTHRC1
Applications Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.09% sodium azide; pH 7.4
Gene Cthrc1
Gene Accession No. Q96CG8
Gene Alias 1110014B07Rik; collagen triple helix repeat containing 1; collagen triple helix repeat-containing protein 1; CTHRC1; Protein NMTC1; UNQ762/PRO1550
Gene Symbols Cthrc1
Host Species Rabbit
Immunogen KLH conjugated synthetic peptide between 19-46 amino acids from the N-terminal region of human CTHRC1.
Purification Method Protein A, Antigen affinity chromatography
Quantity 400 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 115908
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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