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Invitrogen™ CTLA-4 Monoclonal Antibody (1B8), FITC
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Catalog No. 501137435
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500 μg
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50-113-7435 500 μg
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Catalog No. 50-113-7435 Supplier Invitrogen™ Supplier No. HMCD15201
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Armenian Hamster Monoclonal Antibody

CTLA-4 Monoclonal Antibody for ELISA, Flow

CTLA4 (Cytotoxic T-Lymphocyte Antigen 4) is a CD28-family receptor expressed on mainly CD4+ T cells. It binds the same ligands as CD28 (CD80 and CD86 on B cells and dendritic cells), but with higher affinity than CD28. However, in contrast to CD28 which enhances cell function when bound at the same time as the T cell receptor, CTLA4 inhbits the T cell and prevents it from functioning. Intracellular CTLA4 is also found in regulatory T cells and may be important to their function.
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Specifications

Antigen CTLA-4
Applications ELISA, Flow Cytometry
Classification Monoclonal
Clone 1B8
Concentration 0.5 mg/mL
Conjugate FITC
Formulation PBS with <0.1% sodium azide; pH 7.4
Gene CTLA4
Gene Accession No. P09793
Gene Alias ALPS5; CD; CD152; CD152 antigen; CD152 isoform; CD152 protein; CD152 protein precursor; celiac disease 3; CELIAC3; Ctla4; CTLA-4; cytotoxic T lymphocyte associated antigen 4 short spliced form; cytotoxic T-lymphocyte associated protein 4; cytotoxic T-lymphocyte protein 4; cytotoxic T-lymphocyte protein 4 isoform CTLA4-TM; cytotoxic T-lymphocyte-associated antigen 4; cytotoxic T-lymphocyte-associated protein 4; cytotoxic T-lymphocyte-associated serine esterase-4; EGK_04712; GRD4; GSE; ICOS; IDDM12; insulin-dependent diabetes mellitus 12; ligand and transmembrane spliced cytotoxic T lymphocyte associated antigen 4; Ly-56; sCTLA4; soluble form; transmembrane form
Gene Symbols CTLA4
Host Species Armenian Hamster
Immunogen Mouse CD152 (CTLA-4). from Extracellular portion of murine CTLA-4 fused to a murine IgG2a.
Purification Method Purified
Quantity 500 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 12477
Target Species Mouse
Content And Storage 4°C, store in dark
Product Type Antibody
Form Liquid
Isotype IgG1
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WARNING: Reproductive Harm - www.P65Warnings.ca.gov
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