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CTLA4 Mouse anti-Human, Clone: UMAB249, lyophilized, UltraMAB™
SDP

Mouse Monoclonal Antibody

Supplier:  OriGene UM800141CF

Encompass_Preferred

Catalog No. 50-168-5408


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Description

Description

Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No. 7KMWCO

CTLA4 (Cytotoxic T-Lymphocyte Antigen 4) is a CD28-family receptor expressed on mainly CD4+ T cells. It binds the same ligands as CD28 (CD80 and CD86 on B cells and dendritic cells), but with higher affinity. However, in contrast to CD28 which enhances cell function when bound at the same time as the T cell receptor, CTLA4 inhibits the T cell and prevents it from functioning. Intracellular CTLA4 is also found in regulatory T cells and may be important to their function.
Specifications

Specifications

CTLA4
Monoclonal
Unconjugated
CTLA4
ALPS5, CD, CD152, CELIAC3, CTLA-4, GRD4, GSE, IDDM12
Mouse
Affinity Chromatography
RUO
1493
-20° C, Avoid Freeze/Thaw Cycles
Lyophilized
Immunohistochemistry (Paraffin)
UMAB249
PBS with 8% trehalose and no preservative; pH 7.3
P16410
CTLA4
Full length human recombit protein of human CTLA4 produced in HEK293T cell.
100 μg
Primary
Human
Antibody
IgG1
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