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Invitrogen™ CTRP1 Monoclonal Antibody (C2), Invitrogen™
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Catalog No. p-200020281
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200 μL
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FEMA550947 200 μL
FEMA550948 20 μL
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Catalog No. FEMA550947 Supplier Invitrogen™ Supplier No. MA550947
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Description

Mouse Monoclonal Antibody

Adipose tissue of an organism plays a major role in regulating physiologic and pathologic processes such as metabolism and immunity by producing and secreting a variety of bioactive molecules termed adipokines. One highly conserved family of adipokines is adiponectin/ACRP30 and its structural and functional paralogs, the C1q/tumor necrosis factor-alpha-related proteins (CTRPs) 1-7. Unlike adiponectin, which is expressed exclusively by differentiated adipocytes, the CTRPs are expressed in a wide variety of tissues. These proteins are thought to act mainly on liver and muscle tissue to control glucose and lipid metabolism. An analysis of the crystal structure of adiponectin revealed a structural and evolutionary link between TNF and C1q-containing proteins, suggesting that these proteins arose from a common ancestral innate immunity gene. In obese (ob/ob) mice, RT-PCR analysis showed that mCTRP1 transcripts are seen at substantially higher levels in adipose tissues compared to those of normal mice.
TRUSTED_SUSTAINABILITY

Specifications

Antigen CTRP1
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Monoclonal
Clone C2
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.05% Proclin 300; pH 7.4
Gene C1QTNF1
Gene Accession No. Q9BXJ1
Gene Alias 1600017K21Rik; C1q and tumor necrosis factor related protein 1; C1qtnf1; Complement C1q tumor necrosis factor-related protein 1; Ctrp1; G protein coupled receptor interacting protein; g protein-coupled receptor-interacting protein; GIP; putative secreted protein ZSIG37; UNQ310/PRO353; Zsig37
Gene Symbols C1QTNF1
Host Species Mouse
Immunogen Recombinant Human C1QTNF1 protein, Arg26-Pro281 (Accession #Q9BXJ1).
Purification Method Protein A/G
Quantity 200 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 100217377, 114897
Target Species Human, Pig
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG1 κ
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