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Apexbio Technology LLC CU CPT 22 1416324-85-0 25mg
Supplier: Apexbio Technology LLC B575325
CU CPT 22 (CAS 1416324-85-0) is a selective inhibitor of the Toll-like receptor 1/2 (TLR1/2) heterodimer complex This small molecule competitively disrupts the interaction between TLR1/2 and the synthetic triacylated lipopeptide Pam3CSK4 thereby attenuating receptor activation Experimental studies demonstrate that CU CPT 22 reduces Pam3CSK4-induced TLR1/2 signaling in a dose-dependent manner with reported Ki and IC50 values of approximately 0 41 M and 0 58 M respectively CU CPT 22 serves as a valuable tool for investigating the molecular mechanisms underlying TLR1/2 signaling pathways and associated biological processes
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