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Selleck Chemical LLC 4-Methyl-2-oxovaleric acid S2987-1g

Supplier: Selleck Chemical LLC S29871G

4-Methyl-2-oxovaleric acid (Ketoleucine 4-MOV KIC 4-Methyl-2-oxopentanoic acid alpha-Ketoisocaproic acid alpha-ketoisocaproate 2-Oxoisohexanoate) is released by Astrocytes to neurons and can be reaminated by aminotransferase to leucine 4-Methyl-2-oxovaleric acid reduces the rate of protein degradation in skeletal muscle 4-Methyl-2-oxovaleric acid acts as an uncoupler of oxidative phosphorylation (OXPHOS) and as a metabolic inhibitor possibly through its inhibitory effect on alpha-ketoglutarate dehydrogenase (oxoglutarate dehydrogenase complex OGDC) activity
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