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CX3CL1 Mouse anti-Human, Clone: 2F5D5, Proteintech
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Catalog No. 501736426 Shop All Proteintech Group Inc Products
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Catalog No. 50-173-6426 Supplier Proteintech Group Inc Supplier No. 603391IG150UL
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Mouse Monoclonal Antibody

This gene belongs to the CX3C subgroup of chemokines, characterized by the number of amino acids located between the conserved cysteine residues. This is the only member of the CX3C subgroup, which contains three amino acids between cysteine residues, resulting in a Cys-X-X-X-Cys configuration. The encoded protein contains an extended mucin-like stalk with a chemokine domain on top, and exists in both a membrane-anchored form where it acts as a binding molecule, or, in soluble form, as a chemotactic cytokine. The mature form of this protein can be cleaved at the cell surface, yielding different soluble forms that can interact with the G-protein coupled receptor, C-X3-C motif chemokine receptor 1 gene product. This gene plays a role in a wide range of diseases, including cancer, vasculitis, neuropathies, atherosclerosis, inflammatory diseases, and in human immunodeficiency virus infections.

Specifications

Antigen CX3CL1
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Monoclonal
Clone 2F5D5
Concentration 0.7 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene CX3CL1
Gene Accession No. P78423
Gene Alias ABCD 3, C X3 C motif chemokine 1, C3Xkine, CX3CL1, CXC3, CXC3C, FKN, fractalkine, neurotactin, NTN, NTT, SCYD1, Small inducible cytokine D1
Gene Symbols CX3CL1
Host Species Mouse
Immunogen CX3CL1 Fusion Protein Ag0161
Purification Method Protein G
Quantity 150 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 6376
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG1
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