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PeproTech CXCL12 alpha (SDF-1 alpha) Polyclonal Antibody, PeproTech®, Invitrogen™

Catalog No. p-7245288
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500P31550UG 50 μg
500P315100 100 μg
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Catalog No. 500P31550UG Supplier PeproTech Supplier No. 500P31550UG
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Description

Rabbit Polyclonal Antibody

AA Sequence of recombinant protein: KPVSLSYRCP CRFFESHVAR ANVKHLKILN TPNCALQIVA RLKSNNRQVC IDPKLKWIQE YLDKALNK. Preparation: Produced from sera of rabbits immunized with highly pure Recombinant Rat SDF-1alpha (CXCL12). Anti-Rat SDF-1alpha (CXCL12)-specific antibody was purified by affinity chromatography employing an immobilized Rat SDF-1alpha (CXCL12) matrix. Sandwich ELISA: To detect Rat SDF-1alpha (CXCL12) by sandwich ELISA (using 100 μL/well antibody solution), a concentration of 0.5-2.0 μg/mL of this antibody is required. This antigen affinity purified antibody, in conjunction with PeproTech Biotinylated Anti-Rat SDF-1alpha (CXCL12) (500-P315Bt) as a detection antibody, allows the detection of at least 0.2-0.4 ng/well of Recombinant Rat SDF-1alpha (CXCL12). Western Blot: To detect Rat SDF-1alpha by Western Blot analysis this antibody can be used at a concentration of 0.1-0.2 μg/mL. When used in conjunction with compatible secondary reagents, the detection limit for Recombinant Rat SDF-1alpha is 1.5-3.0 ng/lane, under either reducing or non-reducing conditions.

CXCL12 is a stromal cell-derived alpha chemokine member of the intercrine family. This gene product and its receptor CXCR4 can activate lymphocytes and have been implicated in the metastasis of some cancers such as breast cancer. Mutations in this gene are associated with resistance to human immunodeficiency virus type 1 infections. Multiple transcript variants encoding different isoforms have been found for this gene.
TRUSTED_SUSTAINABILITY

Specifications

Antigen CXCL12 alpha (SDF-1 alpha)
Applications ELISA, Western Blot
Classification Polyclonal
Concentration 0.1-1.0 mg/mL
Conjugate Unconjugated
Formulation PBS with no preservative
Gene CXCL12
Gene Accession No. 0
Gene Alias 12-O-tetradecanoylphorbol 13-acetate repressed protein 1; C Cmotif chemokine; C X C motif chemokine; CC motif chemokine; CCmotif chemokine; chemokine (C-X-C motif) ligand 12; chemokine (C-X-C motif) ligand 12 (stromal cell-derived factor 1); CXC; CXC motif chemokine; C-X-C motif chemokine 12; C-X-C motif chemokine ligand 12; CXCL; Cxcl12; H-SDF-1-alpha; Intercrine reduced in hepatomas; IRH; Pbsf; pre-B cell growth-stimulating factor; pre-B-cell growth-stimulating factor; SCYB12; SDF 1 a; SDF 1 alpha; SDF 1α; SDF1; SDF-1; SDF1 alpha; SDF-1 gamma; SDF1A; SDF-1-alpha(3-67); SDF1B; SDF-1-beta(3-72); SDF1α; Stromal cell-derived factor 1; stromal cell-derived factor-1 alpha; stromal cell-derived factor-1 gamma; thymic lymphoma cell-stimulating factor; TLSF; Tpar1
Gene Symbols CXCL12
Host Species Rabbit
Immunogen E.coli-derived Recombinant Rat SDF-1alpha (CXCL12).
Purification Method Antigen affinity chromatography
Quantity 50 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 24772
Target Species Rat
Content And Storage -20°C
Product Type Antibody
Form Lyophilized
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