PeproTech CXCL12 beta (SDF-1 beta) Polyclonal Antibody, Biotin, PeproTech®, Invitrogen™

Catalog No.	Quantity
50-271-8438	500 μg

Catalog No. 50-271-8438 Supplier PeproTech Supplier No. 500P87BGBT500UG

Description

Goat Polyclonal Antibody

AA Sequence of recombinant protein: KPVSLSYRCP CRFFESHVAR ANVKHLKILN TPNCALQIVA RLKNNNRQVC IDPKLKWIQE YLEKALNKRF KM. Preparation: Produced from sera of goats immunized with highly pure Recombinant Human SDF-1beta (CXCL12). Anti-Human SDF-1beta (CXCL12)-specific antibody was purified by affinity chromatography and then biotinylated. Sandwich ELISA: To detect Human SDF-1beta by sandwich ELISA (using 100 μL/well antibody solution) a concentration of 0.25-1.0 μg/mL of this antibody is required. This biotinylated polyclonal antibody, in conjunction with PeproTech Polyclonal Anti-Human SDF-1beta (500-P87BG) as a capture antibody, allows the detection of at least 0.2-0.4 ng/well of Recombinant Human SDF-1beta. Western Blot: To detect Human SDF-1beta by Western Blot analysis this antibody can be used at a concentration of 0.1-0.2 μg/mL. When used in conjunction with compatible secondary reagents, the detection limit for Recombinant Human SDF-1beta is 1.5-3.0 ng/lane, under either reducing or non-reducing conditions. 500-P87BGBT-1MG will be provided as 2 x 500 μg

CXCL12 is a stromal cell-derived alpha chemokine member of the intercrine family. This gene product and its receptor CXCR4 can activate lymphocytes and have been implicated in the metastasis of some cancers such as breast cancer. Mutations in this gene are associated with resistance to human immunodeficiency virus type 1 infections. Multiple transcript variants encoding different isoforms have been found for this gene.

Specifications

• Antigen: CXCL12 beta (SDF-1 beta)
• Applications: ELISA, Western Blot
• Classification: Polyclonal
• Concentration: 0.1-1.0 mg/mL
• Conjugate: Biotin
• Formulation: PBS with no preservative
• Gene: Cxcl12
• Gene Accession No.: P48061
• Gene Alias: 12-O-tetradecanoylphorbol 13-acetate repressed protein 1; C Cmotif chemokine; C X C motif chemokine; CC motif chemokine; CCmotif chemokine; chemokine (C-X-C motif) ligand 12; chemokine (C-X-C motif) ligand 12 (stromal cell-derived factor 1); CXC; CXC motif chemokine; C-X-C motif chemokine 12; C-X-C motif chemokine ligand 12; CXCL; CXCL12; Intercrine reduced in hepatomas; IRH; PBSF; pre-B cell growth-stimulating factor; pre-B-cell growth-stimulating factor; SCYB12; Sdf1; SDF-1; sdf-1 beta; SDF-1 gamma; SDF1A; SDF-1-alpha(3-67); SDF1B; SDF-1-beta(3-72); Stromal cell-derived factor 1; stromal cell-derived factor-1 gamma; thymic lymphoma cell-stimulating factor; TLSF; Tpar1
• Gene Symbols: Cxcl12
• Host Species: Goat
• Immunogen: E.coli-derived, 7.9 kDa Recombinant Human SDF-1beta (CXCL12).
• Purification Method: Antigen affinity chromatography
• Quantity: 500 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 6387
• Target Species: Human
• Content And Storage: -20°C
• Product Type: Antibody
• Form: Lyophilized
• Isotype: IgG