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  5. Tocris Bioscience™ Cyclic Pifithrin-α hydrobromide

Tocris Bioscience™ Cyclic Pifithrin-α hydrobromide
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Catalog No. 384310
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10 mg
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Catalog No. Quantity
38-431-0 10 mg
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Catalog No. 38-431-0 Supplier Tocris Bioscience™ Supplier No. 3843/10
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Description

p53 inhibitor

Cyclic Pifithrin-α hydrobromide is a cyclic analog of pifithrin-α (Cat. No. 1267), a small molecule inhibitor of p53. Prevents dexamethasone -induced cell death in murine thymocytes (EC50 = 2.01 μM). Sensitizes p53-deficient tumors to radiotherapy and chemotherapy; increases apoptosis in target cells when used in combination with antimicrotubule agents.

Chemical Identifiers

CAS 511296-88-1
Molecular Formula C16H17BrN2S

Specifications

Quantity 10 mg
Formula Weight 349.29
Purity >98%
Molecular Weight (g/mol) 349.29
Chemical Name or Material Cyclic Pifithrin-α hydrobromide

Safety and Handling

Recommended Storage Desiccate at Room Temperature
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