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Invitrogen™ Cyclin A1/A2 Recombinant Rabbit Monoclonal Antibody (10O1C8)
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Catalog No. PIMA542789
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100 μL
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PIMA542789 100 μL
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Catalog No. PIMA542789 Supplier Invitrogen™ Supplier No. MA542789
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Description

Rabbit Recombinant Monoclonal Antibody

Positive test controls include: HCT116, Jurkat, Mouse thymus. Immunogen sequence: RGKLQLVGTA AMLLASKFEE IYPPEVAEFV YITDDTYTKK QVLRMEHLVL KVLTFDLAAP TVNQFLTQYF LHQQPANCKV ESLAMFLGEL SLIDADPYLK YLPSVIAGAA FHLALYTVTG QSWPESLIRK TGYTLESLKP CLMDLHQTYL KAPQHAQQSI REKYKNSKYH GVSLLNPPET LNL.

The critical role that the family of regulatory proteins known as cyclins play in eukaryotic cell cycle regulation is well established. The best-characterized cyclin complex is the mitotic cyclin B/Cdc2 p34 kinase, the active component of maturing promoting factor. Cyclin A accumulates prior to cyclin B in the cell cycle, appears to be involved in control of S phase and has been shown to associate with cyclin-dependent kinase-2 (Cdk2). In addition, cyclin A has been implicated in cell transformation and is found in complexes with E1A, transcription factors DRTF1 and E2F and retinoblastoma protein, p110. A second form of cyclin A, named cyclin A1 because of its high sequence homology to Xenopus cyclin A1, is most highly expressed in germ cells. It has been proposed that cyclin A1 can associate with Cdk2, p39 and Cdc2 p34.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Cyclin A1/A2
Applications ELISA, Immunoprecipitation, Western Blot
Classification Recombinant Monoclonal
Clone 10O1C8
Concentration 1.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Gene CCNA2
Gene Accession No. P20248, P51943, P78396, Q61456
Gene Alias AA408589; CCN1; Ccn-1; CCNA; Ccna1; CCNA2; CT146; Cyca; Cyca2; Cyclin A; cyclin A1; cyclin A2; Cyclin A2 (Cyclin A); CyclinA; cyclin-A; CyclinA1; Cyclin-A1; cyclin-A2; testicular tissue protein Li 34
Gene Symbols CCNA1, CCNA2
Host Species Rabbit
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 250-465 of human Cyclin A1/A2 (P20248).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 12427, 12428, 890, 8900
Target Species Human, Mouse
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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