Invitrogen™ Cyclin F Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA536049

Catalog No. PIPA536049

Description

This antibody detects endogenous protein at a molecular weight of 88 kDa. Purity is >95% by SDS-PAGE.

This gene encodes a member of the cyclin family. Cyclins are important regulators of cell cycle transitions through their ability to bind and activate cyclin-dependent protein kinases. This member also belongs to the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class and it was one of the first proteins in which the F-box motif was identified.

Specifications

• Antigen: Cyclin F
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: CCNF
• Gene Alias: CCNF; CDK2; CycF; cyclin F; cyclin-F; EC 2.7.11.22; F-box only protein 1; FBX1; Fbxo1; G2/mitotic-specific cyclin-F; P33(CDK2)
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 117524, 12449, 899
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 0.02% sodium azide; pH 7.2
• Gene Accession No.: P41002, P51944, Q8K4F8
• Gene Symbols: CCNF
• Immunogen: Synthetic peptide corresponding to amino acids 741-786 of Human Cyclin F.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG