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Invitrogen™ Cyclin H Monoclonal Antibody (33TF2-2D4)
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Catalog No. MA3025
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50 μL
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MA3025 50 μL
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Catalog No. MA3025 Supplier Invitrogen™ Supplier No. MA3025
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Description

Mouse Monoclonal Antibody

MA3-025 has been used successfully in Western blotting, Immunoprecipitation and Immunofluorescence applications to detect Cyclin H in human samples.

The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with CDK7 kinase and ring finger protein MAT1. The kinase complex is able to phosphorylate CDK2 and CDC2 kinases, thus functions as a CDK-activating kinase (CAK). This cyclin and its kinase partner are components of TFIIH, as well as RNA polymerase II protein complexes. They participate in two different transcriptional regulation processes, suggesting an important link between basal transcription control and the cell cycle machinery.
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Specifications

Antigen Cyclin H
Applications Immunoprecipitation, Western Blot, Immunocytochemistry
Classification Monoclonal
Clone 33TF2-2D4
Concentration Conc. Not Determined
Conjugate Unconjugated
Formulation ascites with 0.05% sodium azide
Gene CCNH
Gene Accession No. P51946
Gene Alias 6330408H09Rik; AI661354; AV102684; AW538719; CAK; CAK complex subunit; Ccnh; CDK-activating kinase complex subunit; CycH; cyclin H; cyclin-dependent kinase-activating kinase complex subunit; cyclin-H; MO15-associated protein; OTTHUMP00000222395; OTTHUMP00000222396; p34; p37
Gene Symbols CCNH
Host Species Mouse
Immunogen Synthetic peptide (KKRKGYEDDDYVSKKSKHEE) corresponding to aa 292-311 (C-terminal region) of human cyclin H.
Quantity 50 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 902
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG1 κ
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Safety and Handling

WARNING: Reproductive Harm - www.P65Warnings.ca.gov
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