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Invitrogen™ Cyclin H Polyclonal Antibody
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Catalog No. PIPA5105282
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PIPA5105282 100 μL
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Catalog No. PIPA5105282 Supplier Invitrogen™ Supplier No. PA5105282
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total Cyclin H.

The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with CDK7 kinase and ring finger protein MAT1. The kinase complex is able to phosphorylate CDK2 and CDC2 kinases, thus functions as a CDK-activating kinase (CAK). This cyclin and its kinase partner are components of TFIIH, as well as RNA polymerase II protein complexes. They participate in two different transcriptional regulation processes, suggesting an important link between basal transcription control and the cell cycle machinery.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Cyclin H
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene CCNH
Gene Accession No. P51946, Q61458
Gene Alias 6330408H09Rik; AI661354; AV102684; AW538719; CAK; CAK complex subunit; Ccnh; CDK-activating kinase complex subunit; CycH; cyclin H; cyclin-dependent kinase-activating kinase complex subunit; cyclin-H; MO15-associated protein; OTTHUMP00000222395; OTTHUMP00000222396; p34; p37
Gene Symbols CCNH
Host Species Rabbit
Immunogen A synthesized peptide derived from human CCNH(Accession P51946), corresponding to amino acid residues T291-L323.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 66671, 902
Target Species Human, Mouse
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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