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Invitrogen™ Cyclin T1 Polyclonal Antibody
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Catalog No. PIPA577892
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PIPA577892 100 μL
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Catalog No. PIPA577892 Supplier Invitrogen™ Supplier No. PA577892
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Description

Rabbit Polyclonal Antibody

Positive Control: 293T, A431, HeLa, HepG2 Predicted Reactivity: Mouse (86%), Rat (87%), Chimpanzee (100%), Bovine (84%) Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

This gene encodes a member of the highly conserved cyclin C subfamily. The encoded protein tightly associates with cyclin-dependent kinase 9, and is a major subunit of positive transcription elongation factor b (p-TEFb). In humans, there are multiple forms of positive transcription elongation factor b, which may include one of several different cyclins along with cyclin-dependent kinase 9. The complex containing the encoded cyclin and cyclin-dependent kinase 9 acts as a cofactor of human immunodeficiency virus type 1 (HIV-1) Tat protein, and is both necessary and sufficient for full activation of viral transcription. This cyclin and its kinase partner are also involved in triggering transcript elongation through phosphorylation of the carboxy-terminal domain of the largest RNA polymerase II subunit. Overexpression of this gene is implicated in tumor growth. Alternative splicing results in multiple transcript variants.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Cyclin T1
Applications Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1.0 mg/mL
Conjugate Unconjugated
Formulation PBS with 20% glycerol and 0.025% ProClin 300; pH 7
Gene Ccnt1
Gene Accession No. O60563
Gene Alias 2810478G24Rik; AI115585; CCNT; CCNT1; CDK9-associated C-type protein; cyclin C-related protein; cyclin T1; cyclin T1b; cyclin-T; cyclin-T1; CycT1; HIVE1; human immunodeficiency virus type 1 (HIV-1) expression (elevated) 1
Gene Symbols Ccnt1
Host Species Rabbit
Immunogen Recombinant protein encompassing a sequence within the center region of human Cyclin T1. The exact sequence is proprietary.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 315291, 904
Target Species Human, Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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