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Bachem Cyclo(-Arg-Gly-Asp-D-Phe-Val)
SDP

Supplier:  Bachem 4026200.0001

Encompass_Preferred

Cyclo(-Arg-Gly-Asp-D-Phe-Val) Trifluoroacetate, 137813-35-5, C26H38N8O7, Mr 574.64, 1mg. c(RGDfV), EMD 66203, c(Arg-Gly-Asp-DPhe-Val). c(RGDfV) is a potent inhibitor of cell adhesion. It inhibited tumor cell adhesion to laminin and vitronectin substrates. In vivo investigations in rats provided the first evidence of its utility in the amelioration of ischemic acute renal failure. c(RGDfV) inhibited tubular obstruction by preventing cell-cell adhesion. Hammes et al. showed that the cyclopeptide can also be used to prevent retinal neovascularization. c(RGDfV) binds to avb3 receptors.

Catalog No. 50-259-626


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