Invitrogen™ Cyclophilin 40 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA1028

Catalog No. PA1028

Description

PA1-028 detects cyclophilin D (CyPD) in rat, hamster, canine, mouse, and human tissues. PA1-028 has been sucessfully used in Western blot procedures. By Western blot, this antibody detects a ~15 kDa protein in rat liver and heart extract, and a ~37 kDa in rat brain extract. The PA1-028 immunogen is a synthetic peptide corresponding to residues S(42) G N P L V Y L D V D A N(54) C of mature human CyPD. This peptide (Cat. # PEP-104) is available for use in neutralization and control experiments.

This gene encodes a H1 histone binding protein that is involved in transporting histones into the nucleus of dividing cells. Multiple isoforms are encoded by transcript variants of this gene. The somatic form is expressed in all mitotic cells, is localized to the nucleus, and is coupled to the cell cycle. The testicular form is expressed in embryonic tissues, tumor cells, and the testis. In male germ cells, this protein is localized to the cytoplasm of primary spermatocytes, the nucleus of spermatids, and the periacrosomal region of mature spermatozoa.

Specifications

• Antigen: Cyclophilin 40
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: PPID
• Gene Alias: 40 kDa peptidyl-prolyl cis-trans isomerase; 40 kDa peptidyl-prolyl cis-trans isomerase D; 4930564J03Rik; cyclophilin 40; cyclophilin D; cyclophilin-40; Cyclophilin-related protein; Cyp 40; Cyp D; CYP40; CYP-40; CYPD; CYP-S1; cytoplasmic cyclophilin D; EC 5.2.1.8; I79_011990; MGC33096; peptidyl-prolyl cis-trans isomerase D; peptidylprolyl isomerase D; peptidylprolyl isomerase D (cyclophilin D); PPIase; PPIase D; PPID; Ppidl; Ppif; rotamase; Rotamase D; S-cyclophilin; SCYLP; testicular tissue protein Li 147
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 100752921, 361967, 475481, 5481, 67738
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 1mg/mL BSA and 0.05% sodium azide
• Gene Accession No.: Q08752, Q6DGG0, Q9CR16
• Gene Symbols: PPID
• Immunogen: Synthetic peptide corresponding to residues S(42) G N P L V Y L D V D A N(54) C of mature human CyPD.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat, Canine, Hamster
• Product Type: Antibody
• Isotype: IgG