Thermo Scientific Chemicals Cyclosporin A, 98%

Description

Cyclosporin A, 98%, CAS # 59865-13-3, is a compound that shows immunosuppressive, antifungal, antirheumatic, and dermatologic activities. It is also a calcineurin and enzyme inhibitor. | CAS: 59865-13-3 | C62H111N11O12 | 1202.64 g/mol

This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

General Description

• Cyclosporin A is a non-polar cyclic oligopeptide produced by the fungus Tolypocladium inflatum

Specifications

Chemical Identifiers

• CAS: 59865-13-3
• Molecular Formula: C62H111N11O12
• Molecular Weight (g/mol): 1202.64
• MDL Number: MFCD00274558
• InChI Key: PMATZTZNYRCHOR-IMVLJIQENA-N
• PubChem CID: 132274082
• SMILES: CCC1NC(=O)C(C(O)C(C)C\C=C\C)N(C)C(=O)C(C(C)C)N(C)C(=O)C(CC(C)C)N(C)C(=O)C(CC(C)C)N(C)C(=O)C(C)NC(=O)C(C)NC(=O)C(CC(C)C)N(C)C(=O)C(NC(=O)C(CC(C)C)N(C)C(=O)CN(C)C1=O)C(C)C

• Type: Cyclosporin A
• Melting Point: 146.0°C to 151.0°C
• Infrared Spectrum: Authentic
• Loss on Drying: 2% max. (60°C, 3 hrs, 5 mm Hg)
• Quantity: 5 g
• IUPAC Name: (3S,6R,9R,12R,15R,18S,24S,30S,33R)-30-ethyl-33-[(E,1S)-1-hydroxy-2-methylhex-4-enyl]-1,4,7,10,12,15,19,25,28-nonamethyl-6,9,18,24-tetrakis(2-methylpropyl)-3,21-di(propan-2-yl)-1,4,7,10,13,16,19,22,25,28,31-undecazacyclotritriacontane-2,5,8,11,14,17,20,23,
• Formula Weight: 1202.61
• Percent Purity: 98%
• Chemical Name or Material: Cyclosporin A

Frequently Asked Questions (FAQs)

Which solvents can I use to dissolve cyclosporin A, 98%?

Cyclosporin A is soluble in ethanol, chloroform, methylene chloride/dichloromethane, and DMSO.

Safety and Handling

Hazard Category	Danger
Hazard Statement	GHS H Statement Harmful if swallowed. May cause cancer. May damage fertility. May damage the unborn child.
Precautionary Statement	GHS P Statement Wash face, hands and any exposed skin thoroughly after handling. IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell. Obtain special instructions before use. Use personal protective equipment as required. IF exposed or concerned: Get medical advice/attention.

SDS

RUO – Research Use Only