Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
  1. Home
  2. Products
  3. Antibodies
  4. Primary Antibodies
  5. All Primary Antibodies
  6. CYFIP1/2 Rabbit anti-Human, Mouse, Polyclonal, Proteintech 

CYFIP1/2 Rabbit anti-Human, Mouse, Polyclonal, Proteintech
SDP

Catalog No. 501730640 Shop All Proteintech Group Inc Products
Encompass_Preferred
Change view
Click to view available options
Quantity:
150 μL
1 product options available for selection
Product selection table with 1 available options. Use arrow keys to navigate and Enter or Space to select.
Catalog No. Quantity
50-173-0640 150 μL
Use arrow keys to navigate between rows. Press Enter or Space to select a product option. 1 options available.
1 options
Catalog No. 50-173-0640 Supplier Proteintech Group Inc Supplier No. 160111AP150UL
Only null left
Add to Cart
Add to Cart

Description

Rabbit Polyclonal Antibody

This antibody can recognize both CYFIP1 and CYFIP2.

CYFIP2 (Cytoplasmic FMR1-interacting protein 2, p53-inducible protein 121) is a 1, 278 amino acid protein encoded by the human gene CYFIP2. CYFIP2 belongs to the CYFIP family and is involved in T-cell adhesion and p53-dependent induction of apoptosis. It interacts with FMR1, FXR1 and FXR2 and is a component of the WAVE1 complex composed of Abi-2, CYFIP2, C3orf10/HSPC300, NAP125 and WASF1/WAVE1. Upon binding to activated Rac 1, CYFIP2 causes the complex to dissociate, releasing activated WASF1. The CYFIP2 promoter contains a p53-responsive element that confers p53 binding as well as transcriptional activation of a heterologous reporter. Induced expression of CYFIP2 is sufficient for caspase activation and cellular apoptosis, reminiscent of p53 activation.

Specifications

Antigen CYFIP1/2
Applications Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Classification Polyclonal
Concentration 0.19 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene CYFIP1
Gene Accession No. Q5SQX6, Q7L576, Q7TMB8, Q96F07
Gene Alias CYFIP2, KIAA1168, p53 inducible protein 121, PIR121
Gene Symbols Cyfip1, Cyfip2
Host Species Rabbit
Immunogen CYFIP1/2 Fusion Protein Ag8749
Purification Method Antigen Affinity Chromatography
Quantity 150 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 20430, 23191, 26999, 76884
Target Species Human, Mouse
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
Show More Show Less
Product Title
Select an issue

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.