R&D Systems™ Cyno Monkey IFN-alpha/beta R1 (EHH61907) VersaClone cDNA

Catalog No.
RDC2574	10 μg

Catalog No. RDC2574 Supplier R&D Systems™ Supplier No. RDC2574

Description

This shuttle vector contains the complete ORF for the gene of interest, along with a Kozak consensus sequence for optimal translation initiation. It is inserted NotI to AscI. The gene insert is flanked with convenient multiple cloning sites which can be used to easily cut and transfer the gene cassette into your desired expression vector.

• IFNAR1 interferon alpha and beta receptor subunit 1 [ Macaca fascicularis (crabeating macaque) ]
• IFN-alpha/beta R1, also known as IFNAR1, is a 120 kDa component of the class II cytokine receptor that contributes to the functional receptor for type I IFNs
• IFN-alpha/beta R1 associates with the 100 kDa IFN-alpha/beta R2 component to form a receptor complex that transmits anti-viral and anti-proliferative signals
• Down-regulation of the receptor is accomplished by ubiquitination and degradation
• Binding and activation of IFNAR1 stimulates Janus protein kinases, which in turn phosphorylate several proteins, including STAT1 and STAT2. It also functions as an antiviral factor
• The IFN-alpha/beta R1 insert is sequence verified and the entire plasmid DNA and insert translated sequences are provided
• For reasearch use only. Not for use in humans.

Specifications

• Gene: cynoIFNAR1
• Accession Number: EHH61907
• Concentration: 10 μg at 0.2 μg/μL
• Formulation: cDNA is provided in 10 mM Tris-Cl, pH 8.5
• Insert Type: 1693 bp
• Gene ID (Entrez): 3454
• Content And Storage: Store the unopened product at -20°C to -70°C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.
• Species: Cynomolgus Monkey
• Quantity: 10 μg