R&D Systems™ Cyno Monkey SIRP gamma/CD172g (XP_005568591) VersaClone cDNA

Catalog No.
RDC2660	10 μg

Catalog No. RDC2660 Supplier R&D Systems™ Supplier No. RDC2660

Description

This shuttle vector contains the complete ORF for the gene of interest, along with a Kozak consensus sequence for optimal translation initiation. It is inserted NotI to AscI. The gene insert is flanked with convenient multiple cloning sites which can be used to easily cut and transfer the gene cassette into your desired expression vector.

• Signal regulatory protein gamma (SIRP gamma, designated CD172g), also called SIRP beta 2, is a type I transmembrane protein belonging to the SIRP/SHPS (CD172) family within the Ig superfamily.
• SIRP gamma is expressed on T cells, CD56bright NK cells and activated NK cells, but not myeloid cells.
• Like SIRP alpha, it binds CD47, but unlike SIRP alpha, it does not contain an obvious signaling mechanism.
• T cell SIRP gamma may play a role as an accessory protein interacting with CD47-expressing antigen presenting cells, and appears to promote antigen-specific T cell proliferation and costimulate T cell activation.
• The SIRP gamma/CD172g insert is sequence verified and the entire plasmid DNA and insert translated sequences are provided.
• For reasearch use only. Not for use in humans.

Specifications

• Gene: SIRP gamma/CD172g
• Accession Number: XP_005568591
• Concentration: 10 μg at 0.2 μg/μL
• Formulation: cDNA is provided in 10 mM Tris-Cl, pH 8.5
• Insert Type: 1177 bp
• Gene ID (Entrez): 55423
• Gene Alias: bA77C3.1, CD172g, CD172g antigen, FLJ42230, signal-regulatory protein beta 2, Signal-regulatory protein beta-2, signal-regulatory protein gamma, SIRP beta 2, SIRP-b2, SIRPB2CD172 antigen-like family member B, SIRP-beta-2, SIRPG, SIRPgamma, SIRP-gamma
• Content And Storage: Store the unopened product at -20°C to -70°C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.
• Species: Cynomolgus Monkey
• Quantity: 10 μg