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R&D Systems™ Cynomolgus Monkey ITGAV/CD51 (XP_005573729) VersaClone cDNA

Catalog No. RDC2570
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RDC2570 10 μg
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Description

This shuttle vector contains the complete ORF for the gene of interest, along with a Kozak consensus sequence for optimal translation initiation. It is inserted NotI to AscI. The gene insert is flanked with convenient multiple cloning sites which can be used to easily cut and transfer the gene cassette into your desired expression vector.

  • ITGAV integrin subunit alpha V [ Macaca fascicularis (crabeating macaque) ]
  • Integrins are heterodimeric integral cell-surface proteins known to participate in cell adhesion as well as cellsurface mediated signaling, mediating interactions between adhesion molecules on adjacent cells and/or the extracellular matrix (ECM)
  • Although they have no catalytic activity, integrins can be part of multimolecular signaling complexes known as focal adhesions
  • ITGAV undergoes posttranslational cleavage to yield disulfide-linked heavy and light chains that combine with multiple integrin beta chains to form different integrins
  • ITGAV has been shown to heterodimerize with beta 1, beta 3, beta 5, beta 6, and beta 8
  • It is proposed that ITGAV may regulate angiogenesis and cancer progression
  • Integrins have diverse roles in several biological processes including cell migration during development and wound healing, cell differentiation, and apoptosis. Their activities can also regulate the metastatic and invasive potential of tumor cells
  • The Integrin alpha V/CD51 insert is sequence verified and the entire plasmid DNA and insert translated sequences are provided
  • For reasearch use only. Not for use in humans.

Specifications

Gene cynoITGAV
Accession Number XP_005573729
Concentration 10 μg at 0.2 μg/μL
Formulation cDNA is provided in 10 mM Tris-Cl, pH 8.5
Insert Type 3160 bp
Gene ID (Entrez) 3685
Content And Storage Store the unopened product at -20°C to -70°C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.
Species Cynomolgus Monkey
Quantity 10 μg
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