R&D Systems™ Cynomolgus Monkey Lgr5/GPR49 (XP_005571599) VersaClone cDNA

Catalog No.
RDC2547	10 μg

Catalog No. RDC2547 Supplier R&D Systems™ Supplier No. RDC2547

Description

This shuttle vector contains the complete ORF for the gene of interest, along with a Kozak consensus sequence for optimal translation initiation. It is inserted NotI to AscI. The gene insert is flanked with convenient multiple cloning sites which can be used to easily cut and transfer the gene cassette into your desired expression vector.

• LGR5 leucine rich repeat containing G protein-coupled receptor 5 [ Macaca fascicularis (crab-eating macaque) ]
• The Lgr5/GPR49 insert is sequence verified and the entire plasmid DNA and insert translated sequences are provided.
• LGR5 is a member of the G protein-coupled receptor 1 family and is the receptor for R-spondins that mediate the potentiation of Wnt/β-catenin signaling by enhancing Wntinduced LRP6 phosphorylation.
• This receptor is expressed in the gonads, the adrenal gland, and in the brain.
• LGR5 acts as a stem cell marker of the intestinal epithelium and the hair follicle.
• Increased expression of LGR5 has been linked to ovarian, colon and hepatocellular cancers.
• For reasearch use only. Not for use in humans.

Specifications

• Gene: cynoLGR5
• Accession Number: XP_005571599
• Concentration: 10 μg at 0.2 μg/μL
• Formulation: cDNA is provided in 10 mM Tris-Cl, pH 8.5
• Insert Type: 2737 bp
• Gene ID (Entrez): 8549
• Content And Storage: Store the unopened product at -20°C to -70°C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.
• Species: Cynomolgus Monkey
• Quantity: 10 μg