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Invitrogen™ CYP1A1 Polyclonal Antibody
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Catalog No. PA1340
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100 μL
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PA1340 100 μL
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Catalog No. PA1340 Supplier Invitrogen™ Supplier No. PA1340
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Description

Rabbit Polyclonal Antibody

PA1-340 detects cytochrome P450 (P450) 1A1 from human cells. This antibody detects, to a lesser extent, other P450 isoforms. PA1-340 has been successfully used in Western blot procedures. By Western blot, this antibody detects an ~54 kDa protein representing P450 1A1 from MCF-7 cell extract. The PA1-340 immunogen is purified, His-tagged, full length human P450 1A1 fusion protein.

This gene, CYP1A1, encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by some polycyclic aromatic hydrocarbons (PAHs), some of which are found in cigarette smoke. The enzyme's endogenous substrate is unknown; however, it is able to metabolize some PAHs to carcinogenic intermediates. The gene has been associated with lung cancer risk. A related family member, CYP1A2, is located approximately 25 kb away from CYP1A1 on chromosome 15.
TRUSTED_SUSTAINABILITY

Specifications

Antigen CYP1A1
Applications Western Blot, Immunocytochemistry
Classification Polyclonal
Conjugate Unconjugated
Formulation PBS with 0.05% sodium azide
Gene CYP1A1
Gene Accession No. P04798
Gene Alias AHH; AHRR; aromatic compound inducible; aryl hydrocarbon hydroxylase; CP11; CYP; CYP1; Cyp1a1; Cyp1a-1; Cyp1a2; Cyp45c; Cypc45c; CYPIA1; cytochrome P1-450; cytochrome P1-450, dioxin-inducible; cytochrome P450 1A1; cytochrome P450 family 1 subfamily A member 1; cytochrome P450 family 1 subfamily a polypeptide 2; cytochrome P450 form 6; cytochrome P450 subfamily I (aromatic compound-inducible) member A1 (C6 form c) (C6 form c); cytochrome P450 subfamily I, polypeptide 1; cytochrome P450, 1a1; cytochrome P450, 1a1, aromatic compound inducible; cytochrome P450, family 1, subfamily a, polypeptide 1; cytochrome P450, subfamily I (aromatic compound-inducible), member A1 (C6, form c) (C6, form c); cytochrome P450, subfamily I (aromatic compound-inducible), polypeptide 1; cytochrome P450-C; cytochrome P450MT2; Cytochrome P450MT2A; Cytochrome P450MT2B; Cytochrome P450-P1; dioxin-inducible; flavoprotein-linked monooxygenase; Hydroperoxy icosatetraenoate dehydratase; microsomal monooxygenase; P1-450; P450; P450 form 6; P450-1; P450-C; P450DX; P450form6; P-450MC; P450MT2; P450-P1; xenobiotic monooxygenase
Gene Symbols CYP1A1
Host Species Rabbit
Immunogen Purified, His-tagged, full length human P450 1A1 fusion protein.
Purification Method Protein G
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 1543
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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