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Invitrogen™ CYP2B6 Monoclonal Antibody (OTI3D5)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA525882

Catalog No. PIMA525882


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Description

Description

CYP2B6 Monoclonal Antibody for Western Blot, ICC/IF, IHC (P), Flow

This gene, CYP2B6, encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by phenobarbital. The enzyme is known to metabolize some xenobiotics, such as the anti-cancer drugs cyclophosphamide and ifosphamide. Transcript variants for this gene have been described; however, it has not been resolved whether these transcripts are in fact produced by this gene or by a closely related pseudogene, CYP2B7. Both the gene and the pseudogene are located in the middle of a CYP2A pseudogene found in a large cluster of cytochrome P450 genes from the CYP2A, CYP2B and CYP2F subfamilies on chromosome 19q.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

CYP2B6
Monoclonal
1.00 mg/mL
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
P13107, P20813, P24460
Cyp2b3, CYP2B6
Full length human recombinant protein of CYP2B6 produced in HEK293T cell.
100 μL
Primary
Human, Mouse, Rat, Canine, Monkey
Antibody
IgG2a
Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
OTI3D5
Unconjugated
CYP2B6
1,4-cineole 2-exo-monooxygenase; CPB6; CYP2B; CYP2B11; Cyp2b3; Cyp2b-3; CYP2B30; CYP2B6; CYP2B7; CYP2B7P; CYPIIB11; CYPIIB3; CYPIIB6; cytochrome P450 2B11; Cytochrome P450 2B3; cytochrome P450 2B6; cytochrome P450 CYP2B30; cytochrome P450 family 2 subfamily B member 6; cytochrome P-450 IIB; cytochrome P450 IIB1; Cytochrome P450 PBD-2; cytochrome P450, family 2, subfamily B, polypeptide 11; cytochrome P450, family 2, subfamily b, polypeptide 3; cytochrome P450, family 2, subfamily B, polypeptide 6; cytochrome P450, subfamily IIB (phenobarbital-inducible), polypeptide 6; cytochrome P450IIB3; Cytochrome-P450-2B11; EFVM; IIB1; P450
Mouse
Affinity chromatography
RUO
1555, 286953, 474177
-20°C, Avoid Freeze/Thaw Cycles
Liquid
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