Invitrogen™ CYP2C8 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5101311

Catalog No. PIPA5101311

Description

Antibody detects endogenous levels of total Cytochrome P450 2C8.

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by phenobarbital. The enzyme is known to metabolize many xenobiotics, including the anticonvulsive drug mephenytoin, benzo(a)pyrene, 7-ethyoxycoumarin, and the anti-cancer drug taxol. This gene is located within a cluster of cytochrome P450 genes on chromosome 10q24.

Specifications

• Antigen: CYP2C8
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: CYP2C8
• Gene Alias: CPC8; CYP2C8; CYPIIC8; Cytochrome P450 2C8; cytochrome P450 family 2 subfamily C member 8; cytochrome P450 form 1; Cytochrome P450 IIC2; cytochrome P450 MP-12; Cytochrome P450 MP-20; cytochrome P450, family 2, subfamily C, polypeptide 8; cytochrome P450, subfamily IIC (mephenytoin 4-hydroxylase), polypeptide 8; flavoprotein-linked monooxygenase; microsomal monooxygenase; MP-12/MP-20; P450 form 1; P450 IIC2; P450 MP-12/MP-20; s-mephenytoin 4-hydroxylase; xenobiotic monooxygenase
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 1558
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: P10632
• Gene Symbols: CYP2C8
• Immunogen: A synthesized peptide derived from human CYP2C8(Accession P10632), corresponding to amino acid residues E250-E300.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov