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Invitrogen™ CYP2C8 Polyclonal Antibody
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Catalog No. PIPA5101311
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PIPA5101311 100 μL
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Catalog No. PIPA5101311 Supplier Invitrogen™ Supplier No. PA5101311
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total Cytochrome P450 2C8.

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by phenobarbital. The enzyme is known to metabolize many xenobiotics, including the anticonvulsive drug mephenytoin, benzo(a)pyrene, 7-ethyoxycoumarin, and the anti-cancer drug taxol. This gene is located within a cluster of cytochrome P450 genes on chromosome 10q24.
TRUSTED_SUSTAINABILITY

Specifications

Antigen CYP2C8
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene CYP2C8
Gene Accession No. P10632
Gene Alias CPC8; CYP2C8; CYPIIC8; Cytochrome P450 2C8; cytochrome P450 family 2 subfamily C member 8; cytochrome P450 form 1; Cytochrome P450 IIC2; cytochrome P450 MP-12; Cytochrome P450 MP-20; cytochrome P450, family 2, subfamily C, polypeptide 8; cytochrome P450, subfamily IIC (mephenytoin 4-hydroxylase), polypeptide 8; flavoprotein-linked monooxygenase; microsomal monooxygenase; MP-12/MP-20; P450 form 1; P450 IIC2; P450 MP-12/MP-20; s-mephenytoin 4-hydroxylase; xenobiotic monooxygenase
Gene Symbols CYP2C8
Host Species Rabbit
Immunogen A synthesized peptide derived from human CYP2C8(Accession P10632), corresponding to amino acid residues E250-E300.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 1558
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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