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Invitrogen™ CYP2R1 Polyclonal Antibody
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Catalog No. PIPA587927
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PIPA587927 100 μL
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Catalog No. PIPA587927 Supplier Invitrogen™ Supplier No. PA587927
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: VVYDFLSRLI EKASVNRKPQ LPQHFVDAYL DEMDQGKNDP SSTFSKENLI FSVGELIIAG TETTTNVLRW AILFMALYPN IQGQVQKEID LIMGPNGKPS WDDKCKMPYT EAVLHEVLRF CNIVPLGIFH ATSEDAVVRG YSIPKGTTVI TNLYSVHFDE KYWRDPEVFH PERFLDSSGY FAKKEALVPF SLGRRHCLGE HLARMEMFLF FTALLQRFHL HFPHELVPDL KPRLGMTLQP QPYLICAERR; Positive Samples: Mouse testis, Rat liver; Cellular Location: Endoplasmic reticulum membrane, Microsome membrane, Peripheral membrane protein.

CYP2R1 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This enzyme is a microsomal vitamin D hydroxylase that converts vitamin D into the active ligand for the vitamin D receptor. A mutation in CYP2R1 gene has been associated with selective 25-hydroxyvitamin D deficiency.
TRUSTED_SUSTAINABILITY

Specifications

Antigen CYP2R1
Applications ELISA, Western Blot
Classification Polyclonal
Concentration 1.58 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
Gene Cyp2r1
Gene Accession No. Q6VVW9
Gene Alias Cyp2r1; Cytochrome P450 2R1; cytochrome P450 family 2 subfamily R member 1; cytochrome P450, 2r1; cytochrome P450, family 2, R1; cytochrome P450, family 2, subfamily R, polypeptide 1; vitamin D 25-hydroxylase
Gene Symbols Cyp2r1
Host Species Rabbit
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 252-501 of human CYP2R1 (NP_0787902).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 244209, 361631
Target Species Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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