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Invitrogen™ CYP3A5 Monoclonal Antibody (F18 P3 B6)
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Catalog No. 01670130
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100 μL
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Catalog No. Quantity
01-670-130 100 μL
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Catalog No. 01-670-130 Supplier Invitrogen™ Supplier No. MA3033
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Description

Mouse Monoclonal Antibody

MA3-033 detects Cytochrome P450 3A5 from HEK293 and HepG2 human cell lines, and from bovine liver and pancreas samples. MA3-033 has been successfully used in Western blot applications. By Western blot, this antibody detects a ~54 kDa band representing Cytochrome P450 3A5. The MA3-033 immunogen is a synthetic peptide corresponding to residues E S R D G T L S G E, conjugated to ovalbumin.

CYP3A5 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by glucocorticoids and some pharmacological agents. The enzyme metabolizes drugs such as nifedipine and cyclosporine as well as the steroid hormones testosterone, progesterone and androstenedione.
TRUSTED_SUSTAINABILITY

Specifications

Antigen CYP3A5
Applications ELISA, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Monoclonal
Clone F18 P3 B6
Concentration Conc. Not Determined
Conjugate Unconjugated
Formulation Ascites with 0.05% sodium azide
Gene CYP3A5
Gene Accession No. P20815
Gene Alias aryl hydrocarbon hydroxylase; CP35; CYP3A28; CYP3A4; CYP3A5; CYPIIIA28; CYPIIIA5; cytochrome P450; cytochrome P450 3A28; cytochrome P450 3A5; cytochrome P450 family 3 subfamily A member 5; cytochrome P450 HLp2; cytochrome P450, family 3, subfamily A, polypeptide 5; cytochrome P450, subfamily IIIA (niphedipine oxidase), polypeptide 4; cytochrome P450, subfamily IIIA (niphedipine oxidase), polypeptide 5; cytochrome P450-PCN3; flavoprotein-linked monooxygenase; HLp2; microsomal monooxygenase; P450PCN3; P450-PCN3; PCN3; Unknown (protein for MGC:127840); xenobiotic monooxygenase
Gene Symbols CYP3A5
Host Species Mouse
Immunogen Synthetic peptide corresponding to residues E S R D G T L S G E, conjugated to ovalbumin.
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 1577, 282214, 526682
Target Species Bovine, Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG1
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