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Invitrogen™ CYP3A7 Monoclonal Antibody (F19 P2 H2)
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Catalog No. 01670131
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Catalog No. Quantity
01-670-131 100 μL
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Catalog No. 01-670-131 Supplier Invitrogen™ Supplier No. MA3034
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Mouse Monoclonal Antibody

MA3-034 detects Cytochrome P450 3A7 from Human samples and bovine liver samples. MA3-034 has been successfully used in Western blot and Immunohistochemistry (paraffin) applications. By Western blot, this antibody detects a ~54 kDa band representing Cytochrome P450 3A7. The MA3-034 immunogen is a synthetic peptide corresponding to residues E S R D E T V S G A, conjugated to ovalbumin.

This gene, CYP3A7, encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This enzyme hydroxylates testosterone and dehydroepiandrosterone 3-sulphate, which is involved in the formation of estriol during pregnancy. The enzyme also metabolizes some drugs such as aflatoxin B1. This gene is part of a cluster of cytochrome P450 genes on chromosome 7q21.1. Transcript variants have been described, but it is not known whether these transcripts are normally produced.
TRUSTED_SUSTAINABILITY

Specifications

Antigen CYP3A7
Applications ELISA, Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot
Classification Monoclonal
Clone F19 P2 H2
Concentration Conc. Not Determined
Conjugate Unconjugated
Formulation Ascites with 0.05% sodium azide
Gene CYP3A7
Gene Accession No. P24462
Gene Alias aryl hydrocarbon hydroxylase; CP37; CYP3A7; CYPIIIA7; Cytochrome P450 3A7; cytochrome P450 family 3 subfamily A member 7; cytochrome P450, family 3, subfamily A, polypeptide 7; cytochrome P450, subfamily IIIA, polypeptide 7; cytochrome P450-HFLA; flavoprotein-linked monooxygenase; microsomal monooxygenase; P-450(HFL33); P-450111A7; P450-HFLA; P450HLp2; xenobiotic monooxygenase
Gene Symbols CYP3A7
Host Species Mouse
Immunogen Synthetic peptide corresponding to residues E S R D E T V S G A, conjugated to ovalbumin.
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 1551
Target Species Bovine, Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG1
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