Invitrogen™ CYP4F11 Monoclonal Antibody (F21 P6 F5)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA112890

Catalog No. 01-674-091

Description

A suggested positive control for this product is liposarcoma or kidney tissue.

The cytochrome P450 proteins (CYPs) are monooxygenases that catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. P450 enzymes are classified into subfamilies based on their sequence similarities. CYP4F11 is an isoform of the cytochrome P450 4F protein and is expressed mainly in human liver, followed by kidney, heart, and skeletal muscle. CYP4F11 contains 524 amino acid residues that share 80.0, 82.3 and 79.2% identity to CYP4F2, CYP4F3, and CYP4F8 amino acid sequences, respectively. CYP4F11 has catalytic properties towards endogenous eicosanoids as well as some clinically relevant drugs, and is able to metabolize large molecules such as erythromycin.

Specifications

• Antigen: CYP4F11
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 0.08% sodium azide
• Gene Accession No.: Q9HBI6
• Gene Symbols: CYP4F11
• Immunogen: Synthetic peptide corresponding to human CYP450 4F11.
• Quantity: 200 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1

• Applications: ELISA, Immunohistochemistry (Paraffin), Western Blot
• Clone: F21 P6 F5
• Conjugate: Unconjugated
• Gene: CYP4F11
• Gene Alias: 3-hydroxy fatty acids omega-hydroxylase CYP4F11; CYP4F11; CYPIVF11; cytochrome P450 4F11; cytochrome P450 family 4 subfamily F member 11; cytochrome P450, family 4, subfamily F, polypeptide 11; cytochrome P450, subfamily IVF, polypeptide 11; Docosahexaenoic acid omega-hydroxylase; Long-chain fatty acid omega-monooxygenase; Phylloquinone omega-hydroxylase CYP4F11
• Host Species: Mouse
• Purification Method: Protein A/G
• Regulatory Status: RUO
• Gene ID (Entrez): 57834
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid