Invitrogen™ CYP7A1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA515216

Catalog No. PIPA515216

Description

This antibody is predicted to react with rabbit based on sequence homology.

CYP7A1 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum membrane protein catalyzes the first reaction in the cholesterol catabolic pathway in the liver, which converts cholesterol to bile acids. This reaction is the rate limiting step and the major site of regulation of bile acid synthesis, which is the primary mechanism for the removal of cholesterol from the body.

Specifications

• Antigen: CYP7A1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Cyp7a1
• Gene Alias: 24-hydroxycholesterol 7-alpha-hydroxylase; CHAP; cholesterol 7 alpha hydroxylase; cholesterol 7-alpha hydroxylase; cholesterol 7-alpha-hydroxylase; Cholesterol 7-alpha-monooxygenase; CP7A; CYP7; Cyp7a1; CYP7S1; CYPVII; cytochrome P450 (cholesterol hydroxylase 7 alpha); cytochrome P450 7A1; cytochrome P450 family 7 subfamily A member 1; cytochrome P450, 7a1; cytochrome P450, family 7, subfamily a, polypeptide 1; cytochrome P450, subfamily VIIA polypeptide 1
• Host Species: Rabbit
• Purification Method: Ammonium Sulfate Precipitation, Size-exclusion - Dialysis
• Regulatory Status: RUO
• Gene ID (Entrez): 1581
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Western Blot
• Concentration: 2 mg/mL
• Formulation: PBS with 0.09% sodium azide; pH 7.4
• Gene Accession No.: P22680
• Gene Symbols: Cyp7a1
• Immunogen: KLH conjugated synthetic peptide between 476-504 amino acids from the C-terminal region of human CYP7A1.
• Quantity: 400 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG