Invitrogen™ CYP7A1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5119862

Catalog No. PIPA5119862

Description

Positive Control: HepG2 cell lysate, Hela cell lysate, 293T cell lysate, SiHa, Hela. Subcellular Location: Endoplasmic reticulum membrane, Microsome membrane.

CYP7A1 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum membrane protein catalyzes the first reaction in the cholesterol catabolic pathway in the liver, which converts cholesterol to bile acids. This reaction is the rate limiting step and the major site of regulation of bile acid synthesis, which is the primary mechanism for the removal of cholesterol from the body.

Specifications

• Antigen: CYP7A1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Cyp7a1
• Gene Alias: 24-hydroxycholesterol 7-alpha-hydroxylase; CHAP; cholesterol 7 alpha hydroxylase; cholesterol 7-alpha hydroxylase; cholesterol 7-alpha-hydroxylase; Cholesterol 7-alpha-monooxygenase; CP7A; CYP7; Cyp7a1; CYP7S1; CYPVII; cytochrome P450 (cholesterol hydroxylase 7 alpha); cytochrome P450 7A1; cytochrome P450 family 7 subfamily A member 1; cytochrome P450, 7a1; cytochrome P450, family 7, subfamily a, polypeptide 1; cytochrome P450, subfamily VIIA polypeptide 1
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 1581
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Flow Cytometry, Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: TBS with 0.2% BSA, 50% glycerol and 0.05% sodium azide; pH 7.4
• Gene Accession No.: P22680
• Gene Symbols: Cyp7a1
• Immunogen: Recombinant protein within human CYP7A1 aa 50-250.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov