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Invitrogen™ CYP7A1 Polyclonal Antibody
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Catalog No. PIPA5119862
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100 μL
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PIPA5119862 100 μL
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Catalog No. PIPA5119862 Supplier Invitrogen™ Supplier No. PA5119862
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Description

Rabbit Polyclonal Antibody

Positive Control: HepG2 cell lysate, Hela cell lysate, 293T cell lysate, SiHa, Hela. Subcellular Location: Endoplasmic reticulum membrane, Microsome membrane.

CYP7A1 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum membrane protein catalyzes the first reaction in the cholesterol catabolic pathway in the liver, which converts cholesterol to bile acids. This reaction is the rate limiting step and the major site of regulation of bile acid synthesis, which is the primary mechanism for the removal of cholesterol from the body.
TRUSTED_SUSTAINABILITY

Specifications

Antigen CYP7A1
Applications Flow Cytometry, Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation TBS with 0.2% BSA, 50% glycerol and 0.05% sodium azide; pH 7.4
Gene Cyp7a1
Gene Accession No. P22680
Gene Alias 24-hydroxycholesterol 7-alpha-hydroxylase; CHAP; cholesterol 7 alpha hydroxylase; cholesterol 7-alpha hydroxylase; cholesterol 7-alpha-hydroxylase; Cholesterol 7-alpha-monooxygenase; CP7A; CYP7; Cyp7a1; CYP7S1; CYPVII; cytochrome P450 (cholesterol hydroxylase 7 alpha); cytochrome P450 7A1; cytochrome P450 family 7 subfamily A member 1; cytochrome P450, 7a1; cytochrome P450, family 7, subfamily a, polypeptide 1; cytochrome P450, subfamily VIIA polypeptide 1
Gene Symbols Cyp7a1
Host Species Rabbit
Immunogen Recombinant protein within human CYP7A1 aa 50-250.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 1581
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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