Invitrogen™ CYSLTR2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA532717

Catalog No. PIPA532717

Description

Percent identity with other species by BLAST analysis: Human, Gibbon, Marmoset, Horse (100%); Gorilla, Monkey, Mouse, Panda (94%); Dog, Bovine, Hamster, Elephant, Rabbit, Opossum (88%); Pig (82%). For IHC(P), use heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen.

Receptor for cysteinyl leukotrienes. The response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system. Stimulation by BAY u9773, a partial agonist, induces specific contractions of pulmonary veins and might also have an indirect role in the relaxation of the pulmonary vascular endothelium. The rank order of affinities for the leukotrienes is LTC4 = LTD4 >> LTE4.

Specifications

• Antigen: CYSLTR2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: CYSLTR2
• Gene Alias: 2300001H05Rik; Cltr2; CysLT(2); Cyslt2; CysLT-2; CYSLT2R; CYSLTR2; cysteinyl leukotriene CysLT2 receptor; cysteinyl leukotriene receptor 2; GPCR21; G-protein coupled receptor GPCR21; G-protein coupled receptor HG57; HG57; hGPCR21; HPN321; KPG_011; PSEC0146; RSBPT32
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 100056882, 57105
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: ELISA, Immunohistochemistry (Paraffin)
• Concentration: 1 mg/mL
• Formulation: PBS with 0.1% sodium azide
• Gene Accession No.: Q9NS75
• Gene Symbols: CYSLTR2
• Immunogen: Synthetic 17 amino acid peptide from 1st extracellular domain of human CYSLTR2 / CYSLT2.
• Quantity: 50 μg
• Primary or Secondary: Primary
• Target Species: Human, Horse
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

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