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Invitrogen™ Cystatin C Polyclonal Antibody
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Catalog No. PIPA5120379
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PIPA5120379 100 μL
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Catalog No. PIPA5120379 Supplier Invitrogen™ Supplier No. PA5120379
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Description

Rabbit Polyclonal Antibody

Positive test controls include: SKOV3, A-549, BT-474, HeLa, Mouse liver, Mouse testis, Rat brain. The target is usually found in the following locations: Secreted. Immunogen sequence: MAGPLRAPLL LLAILAVALA VSPAAGSSPG KPPRLVGGPM DASVEEEGVR RALDFAVGEY NKASNDMYHS RALQVVRARK QIVAGVNYFL DVELGRTTCT KTQPNLDNCP FHDQPHLKRK AFCSFQIYAV PWQGTMTLSK STCQDA.

Cystatin C, a member of the type 2 cystatin superfamily, is a potent inhibitor of cysteine proteinases, both endogenous (lysosomal cathepsins), and pathogenic. Cystatin C is a 13 kDa secreted protein which is found in high concentrations in biological fluids and is thought to be expressed by all human nucleated cells. Changes in Cystatin C have been documented in a number of cardiovascular diseases, including atherosclerosis, amyloid angiopathy and myocardial infarction. Its low molecular weight also means that Cystatin C can be used as a marker of renal failure.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Cystatin C
Applications ELISA, Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 0.58 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.05% ProClin 300; pH 7.3
Gene Cst3
Gene Accession No. P01034, P14841, P21460
Gene Alias AD8; ARMD11; bA218C14.4 (cystatin C); CST3; CYSC; cystatin; cystatin 3; cystatin C; cystatin C (amyloid angiopathy and cerebral hemorrhage); Cystatin C (cysteine proteinase inhibitor); Cystatin3; cystatin-3; CystatinC; Cystatin-C; epididymis secretory protein Li 2; fb51d07; Gamma-trace; HEL-S-2; MGC117328; neuroendocrine basic polypeptide; OTTHUMP00000030440; OTTHUMP00000164181; OTTHUMP00000164182; OTTMUSP00000016736; Post-gamma-globulin; RP23-250M11.9; wu:fb24g06; wu:fb51d07; wu:fc55f03; zgc:136227
Gene Symbols Cst3
Host Species Rabbit
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 1-146 of human Cystatin C (NP_0000901).
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 13010, 1471, 25307
Target Species Human, Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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