Invitrogen™ Cystatin C Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5120379

Catalog No. PIPA5120379

Description

Positive test controls include: SKOV3, A-549, BT-474, HeLa, Mouse liver, Mouse testis, Rat brain. The target is usually found in the following locations: Secreted. Immunogen sequence: MAGPLRAPLL LLAILAVALA VSPAAGSSPG KPPRLVGGPM DASVEEEGVR RALDFAVGEY NKASNDMYHS RALQVVRARK QIVAGVNYFL DVELGRTTCT KTQPNLDNCP FHDQPHLKRK AFCSFQIYAV PWQGTMTLSK STCQDA.

Cystatin C, a member of the type 2 cystatin superfamily, is a potent inhibitor of cysteine proteinases, both endogenous (lysosomal cathepsins), and pathogenic. Cystatin C is a 13 kDa secreted protein which is found in high concentrations in biological fluids and is thought to be expressed by all human nucleated cells. Changes in Cystatin C have been documented in a number of cardiovascular diseases, including atherosclerosis, amyloid angiopathy and myocardial infarction. Its low molecular weight also means that Cystatin C can be used as a marker of renal failure.

Specifications

• Antigen: Cystatin C
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Cst3
• Gene Alias: AD8; ARMD11; bA218C14.4 (cystatin C); CST3; CYSC; cystatin; cystatin 3; cystatin C; cystatin C (amyloid angiopathy and cerebral hemorrhage); Cystatin C (cysteine proteinase inhibitor); Cystatin3; cystatin-3; CystatinC; Cystatin-C; epididymis secretory protein Li 2; fb51d07; Gamma-trace; HEL-S-2; MGC117328; neuroendocrine basic polypeptide; OTTHUMP00000030440; OTTHUMP00000164181; OTTHUMP00000164182; OTTMUSP00000016736; Post-gamma-globulin; RP23-250M11.9; wu:fb24g06; wu:fb51d07; wu:fc55f03; zgc:136227
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 13010, 1471, 25307
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Western Blot, Immunocytochemistry
• Concentration: 0.58 mg/mL
• Formulation: PBS with 50% glycerol and 0.05% ProClin 300; pH 7.3
• Gene Accession No.: P01034, P14841, P21460
• Gene Symbols: Cst3
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-146 of human Cystatin C (NP_0000901).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG