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Cayman Chemical 25I-NBFhydrochlorIde 5mg

Supplier: Cayman Chemical 140665 MG
A cGMP phosphodiesterase inhibitor (IC50s 0 5-0 76 and 0 15 UM for PDE5 and PDE6 respectively) selective for PDE5 and PDE6 over PDE9 PDE10 and PDE11 (IC50s 35 22 and 11-33 UM respectively) enhances the vasodilatory effects of NO in a range of vascular tissues by prolonging the cGMP-mediated activation of cGMP-dependent protein kinase activates both rat and human GPR35 (EC50s 16 nM and 0 84 UM respectively)
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