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Invitrogen™ Cytochrome C Monoclonal Antibody (6H2.B4), Alexa Fluor™ 647
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Catalog No. PIMA33820AY
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50 μL
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PIMA33820AY 50 μL
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Catalog No. PIMA33820AY Supplier Invitrogen™ Supplier No. MA338200A647
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Mouse Monoclonal Antibody

This antibody reacts with native Cytochrome C, but does not recognize denatured cytochrome C. The antibody recognizes a region in the vicinity of amino acid 62 of rat Cytochrome C.

Cytochrome C is an electron transporting protein that resides within the intermembrane space of the mitochondria, where it plays a critical role in oxidative phosphorylation and the production of cellular ATP. Release of cytochrome C from the mitochondria to the cytosol is triggered by apoptotic stimuli. In the cytoplasm, the cytochrome C binds apoptotic protease activating factor which activates the apoptotic initiator procaspase 9. Cytosolic cytochrome C functions in the activation of caspase 3, an ICE family molecule that is a key effector of apoptosis.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Cytochrome C
Applications Immunocytochemistry
Classification Monoclonal
Clone 6H2.B4
Concentration 1 mg/mL
Conjugate Alexa Fluor 647
Formulation PBS with 1mg/mL BSA and 0.05% sodium azide; pH 7.4
Gene Cycs
Gene Accession No. P62897, P62898, P84029, P99999
Gene Alias APOCYTOCHROME C-A; AT1G22840; AT4G10040; ATCYTC-A; CG17903; CG17903-PA; CG17903-PB; CRF; CYC; CYC2; Cycs; CYCSA; Cyct-c-p; Cyt c; cyt c-p; cyt.c; CytC; Cyt-c; CYTC-1; CYTC2; Cyt-c2; CytC-2; cyt-c-p; cytC-p; Cyt-c-p-PA; Cyt-c-p-PB; Cytochrome c; cytochrome c DC4; Cytochrome c proximal; Cytochrome C, expressed in somatic tissues; cytochrome c, somatic; CYTOCHROME C-1; CYTOCHROME C-2; CYTOCHROME C-A; cytochrome c-like; cytochrome c-like protein; Cytochrome c-proximal; cytochrome-c-p; Cytochrome-c-proximal; DC4; dCyt.C-p; DMc01; Dmel\CG17903; Dmel_CG17903; F19G10.20; F19G10_20; hc1; HCS; l(2)k13905; lethal (2) k13905; LOC100341175; LOC100357840; MGC128356 protein; pDMc01; RH17228p; T5L19.170; T5L19_170; THC4
Gene Symbols Cycs, Cyt-c-p, LOC100341175, LOC100357840
Host Species Mouse
Immunogen Rat cytochrome C.
Purification Method Protein A
Quantity 50 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 100341175, 100357840, 13063, 25309, 34996, 54205
Target Species Drosophila, Human, Mouse, Rabbit, Rat
Content And Storage 4°C, store in dark, DO NOT FREEZE!
Product Type Antibody
Form Liquid
Isotype IgG1 κ
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