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Invitrogen™ Cytochrome C Monoclonal Antibody (7H8.2C12)
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Catalog No. PIMA511674
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500 μL
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PIMA511674 500 μL
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Catalog No. PIMA511674 Supplier Invitrogen™ Supplier No. MA511674
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Description

Mouse Monoclonal Antibody

MA5-11674 targets Cytochrome c in IHC (P) and WB applications and shows reactivity with Human, mouse, and Rat samples. The MA5-11674 immunogen is synthetic peptides corresponding to amino acids 1-80, 81-104 and 66-104 of pigeon cytochrome c.

Cytochrome C is an electron transporting protein that resides within the intermembrane space of the mitochondria, where it plays a critical role in oxidative phosphorylation and the production of cellular ATP. Release of cytochrome C from the mitochondria to the cytosol is triggered by apoptotic stimuli. In the cytoplasm, the cytochrome C binds apoptotic protease activating factor which activates the apoptotic initiator procaspase 9. Cytosolic cytochrome C functions in the activation of caspase 3, an ICE family molecule that is a key effector of apoptosis.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Cytochrome C
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Monoclonal
Clone 7H8.2C12
Concentration 0.2 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.05% BSA and 0.05% sodium azide; pH 7.4
Gene Cycs
Gene Accession No. P62897, P99999
Gene Alias CG17903; CG17903-PA; CG17903-PB; CRF; CYC; CYC2; Cycs; CYCSA; Cyct-c-p; Cyt c; cyt c-p; cyt.c; CytC; Cyt-c; CYTC2; Cyt-c2; CytC-2; cyt-c-p; cytC-p; Cyt-c-p-PA; Cyt-c-p-PB; Cytochrome c; cytochrome c DC4; Cytochrome c proximal; Cytochrome C, expressed in somatic tissues; cytochrome c, somatic; Cytochrome c-2; cytochrome c-like; cytochrome c-like protein; Cytochrome c-proximal; cytochrome-c-p; Cytochrome-c-proximal; DC4; dCyt.C-p; DMc01; Dmel\CG17903; Dmel_CG17903; hc1; HCS; l(2)k13905; lethal (2) k13905; LOC100341175; LOC100357840; MGC128356 protein; pDMc01; RH17228p; THC4
Gene Symbols Cycs
Host Species Mouse
Immunogen Synthetic peptides corresponding to amino acids 1-80, 81-104 and 66-104 of pigeon cytochrome c.
Purification Method Protein A/G
Quantity 500 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 13063, 54205
Target Species Human, Mouse
Content And Storage 4°C
Product Type Antibody
Form Liquid
Isotype IgG2b κ
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