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Invitrogen™ Cytochrome C Polyclonal Antibody
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Catalog No. 01674462
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Catalog No. Quantity
01-674-462 100 μg
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Catalog No. 01-674-462 Supplier Invitrogen™ Supplier No. PA19586
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Description

Rabbit Polyclonal Antibody

PA1-9586 detects Cytochrome C in human, mouse, bovine and rat samples. PA1-9586 has been successfully used in Western blot and ELISA procedures. By Western blot, PA1-9586 detects a 12 kDa protein representing Cytochrome C. Do not use dry milk in blocking or dilution buffer in your assay. Use BSA (3-5% in blocking and 1-3% in dilution buffers) in your assay. PA1-9586 immunogen is a purified bovine cytochrome c protein Store at 4ºC for 1 week, and -20ºC for up to one year.

Cytochrome C is an electron transporting protein that resides within the intermembrane space of the mitochondria, where it plays a critical role in oxidative phosphorylation and the production of cellular ATP. Release of cytochrome C from the mitochondria to the cytosol is triggered by apoptotic stimuli. In the cytoplasm, the cytochrome C binds apoptotic protease activating factor which activates the apoptotic initiator procaspase 9. Cytosolic cytochrome C functions in the activation of caspase 3, an ICE family molecule that is a key effector of apoptosis.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Cytochrome C
Applications ELISA, Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.02% sodium azide
Gene Cycs
Gene Accession No. P62894, P62897, P62898, P99999
Gene Alias CG17903; CG17903-PA; CG17903-PB; CRF; CYC; CYC2; Cycs; CYCSA; Cyct-c-p; Cyt c; cyt c-p; cyt.c; CytC; Cyt-c; CYTC2; Cyt-c2; CytC-2; cyt-c-p; cytC-p; Cyt-c-p-PA; Cyt-c-p-PB; Cytochrome c; cytochrome c DC4; Cytochrome c proximal; Cytochrome C, expressed in somatic tissues; cytochrome c, somatic; Cytochrome c-2; cytochrome c-like; cytochrome c-like protein; Cytochrome c-proximal; cytochrome-c-p; Cytochrome-c-proximal; DC4; dCyt.C-p; DMc01; Dmel\CG17903; Dmel_CG17903; hc1; HCS; l(2)k13905; lethal (2) k13905; LOC100341175; LOC100357840; MGC128356 protein; pDMc01; RH17228p; THC4
Gene Symbols Cycs
Host Species Rabbit
Immunogen Purified bovine cytochrome c protein.
Purification Method Affinity Chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 13063, 25309, 510767, 54205
Target Species Human, Mouse, Rat, Bovine
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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