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Invitrogen™ Cytokeratin 14 Monoclonal Antibody (LL002)
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Catalog No. PIMA511599
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500 μL
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Catalog No. Quantity
PIMA511599 500 μL
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Catalog No. PIMA511599 Supplier Invitrogen™ Supplier No. MA511599
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Description

Mouse Monoclonal Antibody

MA5-11599 targets Cytokeratin 14 in IHC (P) and WB applications and shows reactivity with Human and Rat samples. The MA5-11599 immunogen is a synthetic peptide of 15 amino acid residues from the C-terminus of human keratin 14.

Cytokeratins (CK) are intermediate filaments of epithelial cells, both in keratinizing tissue (ie. skin) and non-keratinizing cells (ie. mesothelial cells). At least 20 different CKs can be identified. Biochemically, most members of the CK family fall into one of two classes, type I (acidic polypeptides) and type II (basic polypeptides). Belonging to the type I subfamily of low molecular weight keratins and existing in combination with keratin 5, keratin 14 distinguishes stratified epithelial cells from simple epithelial cells and is useful in identification of squamous cell carcinomas. It is considered a prognostic marker in breast carcinomas. At least one member of the acidic family and one member of the basic family is expressed in all epithelial cells.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Cytokeratin 14
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry, Multiplex Immunohistochemistry
Classification Monoclonal
Clone LL002
Concentration 0.2 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.05% BSA and 0.05% sodium azide; pH 7.4
Gene KRT14
Gene Accession No. P02533, Q61781, Q6IFV1
Gene Alias AI626930; CK14; CK-14; cytokeratin 14; cytokeratin-14; EBS3; EBS4; epidermolysis bullosa simplex, Dowling-Meara, Koebner; K14; Ka14; keratin 14; keratin 14 (epidermolysis bullosa simplex, Dowling-Meara, Koebner); keratin 14, type I; keratin complex 1, acidic, gene 14; keratin, type I cytoskeletal 14; keratin, type I cytoskeletal 17; keratin-14; Koebner; Krt-1.14; Krt1-14; KRT14; LOC100737113; NFJ; Type I keratin Ka14
Gene Symbols KRT14
Host Species Mouse
Immunogen A synthetic peptide of 15 amino acid residues from the C-terminus of human keratin 14.
Purification Method Protein A/G
Quantity 500 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 16664, 287701, 3861
Target Species Human, Mouse, Rat
Content And Storage 4°C
Product Type Antibody
Form Liquid
Isotype IgG3 κ
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