Invitrogen™ Cytokeratin 14 Monoclonal Antibody (LL002), FITC

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA528125

Catalog No. PIMA528125

Description

Cytokeratin 14 Monoclonal Antibody for ICC/IF, Flow

Cytokeratins (CK) are intermediate filaments of epithelial cells, both in keratinizing tissue (ie. skin) and non-keratinizing cells (ie. mesothelial cells). At least 20 different CKs can be identified. Biochemically, most members of the CK family fall into one of two classes, type I (acidic polypeptides) and type II (basic polypeptides). Belonging to the type I subfamily of low molecular weight keratins and existing in combination with keratin 5, keratin 14 distinguishes stratified epithelial cells from simple epithelial cells and is useful in identification of squamous cell carcinomas. It is considered a prognostic marker in breast carcinomas. At least one member of the acidic family and one member of the basic family is expressed in all epithelial cells.

Specifications

• Antigen: Cytokeratin 14
• Classification: Monoclonal
• Concentration: 0.1 mg/mL
• Formulation: PBS with 1% BSA and 0.09% sodium azide
• Gene Accession No.: P02533
• Gene Symbols: KRT14
• Immunogen: Last 15 C-terminal residues of human cytokeratin 14 conjugated to thyroglobulin.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG3

• Applications: Flow Cytometry, Immunocytochemistry
• Clone: LL002
• Conjugate: FITC
• Gene: KRT14
• Gene Alias: AI626930; CK14; CK-14; cytokeratin 14; cytokeratin-14; EBS3; EBS4; epidermolysis bullosa simplex, Dowling-Meara, Koebner; K14; Ka14; keratin 14; keratin 14 (epidermolysis bullosa simplex, Dowling-Meara, Koebner); keratin 14, type I; keratin complex 1, acidic, gene 14; keratin, type I cytoskeletal 14; keratin, type I cytoskeletal 17; keratin-14; Koebner; Krt-1.14; Krt1-14; KRT14; LOC100737113; NFJ; Type I keratin Ka14
• Host Species: Mouse
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 3861
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Store in the dark.
• Form: Liquid