Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
  1. Home
  2. Products
  3. Antibodies
  4. Primary Antibodies
  5. All Primary Antibodies
  6. PIMA528576

Invitrogen™ Cytokeratin 19 Monoclonal Antibody (A53-B/A2), FITC
GREENER_CHOICE

Catalog No. PIMA528576
Change view
Click to view available options
Quantity:
100 μg
1 product options available for selection
Product selection table with 1 available options. Use arrow keys to navigate and Enter or Space to select.
Catalog No. Quantity
PIMA528576 100 μg
Use arrow keys to navigate between rows. Press Enter or Space to select a product option. 1 options available.
1 options
Catalog No. PIMA528576 Supplier Invitrogen™ Supplier No. MA528576
Only null left
Add to Cart
Edge
Add to Cart

Description

Mouse Monoclonal Antibody

This antibody recognizes the rod domain of cytokeratin 19 (40 kDa), an intracellular antigen constituting intermediate cytoskeleton filaments. Cytokeratin 19 is not expressed in hepatocytes; it is often co-expressed with cytokeratin 7.

Cytokeratin 19 is part of a subfamily of intermediate filament proteins and are characterized by a remarkable biochemical diversity, represented in human epithelial tissues by at least 20 different polypeptides. Cytokeratins range in molecular weight from 40-68 kDa and isoelectric pH between 4.9 - 7.8. The individual human cytokeratins are numbered 1 to 20. The various epithelia in the human body usually express cytokeratins which are not only characteristic of the type of epithelium, but also related to the degree of maturation or differentiation within an epithelium. Cytokeratin subtype expression patterns are used to an increasing extent in the distinction of different types of epithelial malignancies. The cytokeratin antibodies are not only of assistance in the differential diagnosis of tumors using immunohistochemistry on tissue sections, but are also a useful tool in cytopathology and flow cytometric assays. For example, cytokeratin 19 is not expressed in hepatocytes, therefore, it is useful in the identification of liver metastasis.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Cytokeratin 19
Applications Flow Cytometry
Classification Monoclonal
Clone A53-B/A2
Concentration 1 mg/mL
Conjugate FITC
Formulation PBS with 15mM sodium azide; pH 7.4
Gene KRT19
Gene Accession No. P08727
Gene Alias 40-kDa keratin intermediate filament; AI663979; C K1CS; CK 19; CK19; CK-19; cytokeratin 19; cytokeratin-19; EndoC; K19; K1CS; Ka19; keratin 19; keratin 19, type I; keratin complex 1, acidic, gene 19; keratin, type I cytoskeletal 19; keratin, type I, 40-kd; keratin-19; Krt-1.19; Krt1-19; Krt19; LOC100344434; MGC15366; Type I keratin Ka19
Gene Symbols KRT19
Host Species Mouse
Immunogen MCF-7 human breast adenocarcinoma cell line.
Purification Method Size-exclusion chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 3880
Target Species Human
Content And Storage 4°C, store in dark, DO NOT FREEZE!
Product Type Antibody
Form Liquid
Isotype IgG2a
Show More Show Less
Product Title
Select an issue

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.